5-HT receptors expressed throughout the human body are targets for established
therapeutics and various drugs in development. Their diversity of structure and function …

Interleukin-13 receptor subunit alpha-2 (IL-13Rα2, CD213A), a high-affinity membrane
receptor of the anti-inflammatory Th2 cytokine IL-13, is overexpressed in a variety of solid …

The solute carrier (SLC) SLC16 gene family comprises 14 members and encodes for
monocarboxylate transporters (MCTs), which mediate the absorption and distribution of …

The evaluation and categorization of adrenocortical neoplasms remain among the most
challenging areas in adrenal pathology. The Weiss system, first introduced 25 years ago …

BACKGROUND: The authors are interested in identifying molecular markers that can aid in
the diagnosis of adrenocortical carcinoma (ACC). The aim of this study was to identify …

Infiltration of specialized immune cells regulates the growth and survival of neoplasia. Here,
in a survey of public whole genome expression datasets we found that the gene for …

Purpose: The success of immunotherapy for the treatment of metastatic cancer is contingent
on the identification of appropriate target antigens. Potential targets must be expressed on …

The human adrenal cortex secretes mineralocorticoids, glucocorticoids and adrenal
androgens. These steroids are produced from unique cell types located within the three …

Chemerin is widely recognized as an adipokine, with diverse biological roles in cellular
differentiation and metabolism, as well as a leukocyte chemoattractant. Research …

Approximately one-tenth of the general population exhibit adrenal cortical nodules, and the
incidence has increased. Afflicted patients display a multifaceted symptomatology …