Autophagy is a core molecular pathway for the preservation of cellular and organismal
homeostasis. Pharmacological and genetic interventions impairing autophagy responses …

Autophagy is a highly conserved process that degrades certain intracellular contents in both
physiological and pathological conditions. Autophagy-related proteins (ATG) are key players …

CNS-resident macrophages—including parenchymal microglia and border-associated
macrophages (BAMs)—contribute to neuronal development and health, vascularization, and …

The central nervous system (CNS) is under close surveillance by immune cells, which
mediate tissue homeostasis, protection, and repair. Conversely, in neuroinflammation …

Multiple sclerosis (MS) is a chronic progressive demyelinating disease of the central
nervous system (CNS) due to an increase of abnormal peripherally auto-reactive T …

Autophagy comprises a growing range of cellular pathways, which occupy central roles in
response to energy deprivation, organelle turnover and proteostasis. Over the years …

Autophagy, an intracellular conserved degradative process, plays a central role in the
renewal/recycling of a cell to maintain the homeostasis of nutrients and energy within the …

Macroautophagy/autophagy is an evolutionally conserved catabolic process in which
cytosolic contents, such as aggregated proteins, dysfunctional organelle, or invading …

Herpes simplex keratitis (HSK) results from an infection with the herpes simplex virus type 1
(HSV-1) also known as human herpesvirus type 1 (HHV-1). Primary infection may involve an …

Multiple sclerosis (MS) is a neuroinflammatory and neurodegenerative disease
characterized by myelin damage followed by axonal and ultimately neuronal loss. The …