Regulation of gene expression plays a central role in adaptive divergence and evolution.
Although the role of gene regulation in microevolutionary processes is gaining wide …

Intron retention (IR) is a form of alternative splicing that has long been neglected in
mammalian systems although it has been studied for decades in non-mammalian species …

Background Alternative splicing (AS) is a widespread regulatory mechanism in multicellular
organisms. Numerous transcriptomic and single-gene studies in plants have investigated AS …

Translation is pervasive outside of canonical coding regions, occurring in long noncoding
RNAs, canonical untranslated regions and introns,,–, especially in ageing …

The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

Although alternative splicing is a ubiquitous co‐transcriptional gene regulatory mechanism
in plants, animals and fungi, its contribution to evolutionary transitions is understudied …

Adult stem cells are essential for tissue regeneration. However, the mechanisms underlying
the activation of quiescent adult stem cells remain elusive. Using skeletal muscle stem cells …

Intron retention (IR) by alternative splicing is a conserved regulatory mechanism that can
affect gene expression and protein function during adult development and age‐onset …

Early-life antibiotic exposure perturbs the intestinal microbiota and accelerates type 1
diabetes (T1D) development in the NOD mouse model. Here, we found that maternal cecal …

IκBζ (encoded by NFKBIZ) is the most recently identified IkappaB family protein. As an
atypical member of the IkappaB protein family, NFKBIZ has been the focus of recent studies …