Extracellular vesicles (EVs) are membrane vesicles released by both eukaryotic and
prokaryotic cells; they not only serve physiological functions, such as disposal of cellular …

Exosomes are secreted extracellular vesicles (EVs) that carry micro RNAs and other factors
to reprogram cancer cells and tissues affected by cancer. Exosomes are exchanged …

Simple Summary The involvement of leptin and adiponectin with receptors in the formation
of many types of cancer as well as their impact on the clinical course of cancer patients are …

Viral infections are a major health problem; therefore, there is an urgent need for novel
therapeutic strategies. Antivirals used to target proteins encoded by the viral genome usually …

Metabolic reprogramming of cancer cells within the tumor microenvironment typically occurs
in response to increased nutritional, translation and proliferative demands. Altered lipid …

Background Rheumatoid arthritis (RA) is an angiogenesis-dependent disease caused by
the imbalance of pro-and anti-angiogenic factors. More effective strategies to block synovial …

Colorectal cancer (CRC) is among the topmost malignancies for both genders. Despite the
high incidence rate and advances in diagnostic tools, treatment in many cases is still …

Simple Summary Cuproptosis is a newly discovered copper-dependent cell death. We
aimed to explore the functions of cuproptosis in the tumor microenvironment and construct a …

Sphingolipids are well-recognized critical components in several biological processes.
Ceramides constitute a class of sphingolipid metabolites that are involved in important …

Lipid phosphate phosphatases (LPPs) are a group of three enzymes (LPP1–3) that belong
to a phospholipid phosphatase (PLPP) family. The LPPs dephosphorylate a wide spectrum …