Pain associated with mechanical, chemical, and thermal heat stimulation of the ocular
surface is mediated by trigeminal ganglion neurons, while cold thermoreceptors detect …

Neurotrophic Keratopathy (NK) refers to a condition where corneal epitheliopathy leading to
frank epithelial defect with or without stromal ulceration (melting) is associated with reduced …

Dry eye can be caused by a variety of iatrogenic interventions. The increasing number of
patients looking for eye care or cosmetic procedures involving the eyes, together with a …

The cornea is the most sensitive structure in the human body. Corneal nerves adapt to
maintain transparency and contribute to corneal health by mediating tear secretion and …

In vivo confocal microscopy (IVCM) is becoming an indispensable tool for studying corneal
physiology and disease. Enabling the dissection of corneal architecture at a cellular level …

The tear film represents the interface between the eye and the environment. The alteration of
the delicate balance that regulates the secretion and distribution of the tear film determines …

Keratoconus is the most common primary corneal ectasia characterized by progressive focal
thinning. Patients experience increased irregular astigmatism, decreased visual acuity and …

Purpose: The subbasal nerve plexus (SNP) is the densest and most recognizable
component of the mammalian corneal innervation; however, the anatomical configuration of …

Purpose To investigate corneal sensitivity to selective mechanical, chemical, and thermal
stimulation and to evaluate their relation to dry eye symptoms in patients with keratoconus …

Purpose: To investigate the morphologic changes in the corneal subbasal nerve (CSN)
plexus in wild-type mice after exposure to environmental dry eye stress (EDES) using in vivo …