Virus-like particles: preparation, immunogenicity and their roles as nanovaccines and drug nanocarriers
S Nooraei, H Bahrulolum, ZS Hoseini… - Journal of …, 2021 - Springer
Virus-like particles (VLPs) are virus-derived structures made up of one or more different
molecules with the ability to self-assemble, mimicking the form and size of a virus particle but …
molecules with the ability to self-assemble, mimicking the form and size of a virus particle but …
Virus-like particle vaccinology, from bench to bedside
MO Mohsen, MF Bachmann - Cellular & molecular immunology, 2022 - nature.com
Virus-like particles (VLPs) have become key tools in biology, medicine and even
engineering. After their initial use to resolve viral structures at the atomic level, VLPs were …
engineering. After their initial use to resolve viral structures at the atomic level, VLPs were …
Virus-like particles: Revolutionary platforms for developing vaccines against emerging infectious diseases
Virus-like particles (VLPs) are nanostructures that possess diverse applications in
therapeutics, immunization, and diagnostics. With the recent advancements in biomedical …
therapeutics, immunization, and diagnostics. With the recent advancements in biomedical …
Clinical delivery of circular RNA: lessons learned from RNA drug development
Circular RNAs (circRNA) represent a distinct class of covalently closed-loop RNA molecules,
which play diverse roles in regulating biological processes and disease states. The …
which play diverse roles in regulating biological processes and disease states. The …
Interaction between virus-like particles (VLPs) and pattern recognition receptors (PRRs) from dendritic cells (DCs): toward better engineering of VLPs
J Zepeda-Cervantes, JO Ramírez-Jarquín… - Frontiers in …, 2020 - frontiersin.org
Virus-like particles (VLPs) have been shown to be strong activators of dendritic cells (DCs).
DCs are the most potent antigen presenting cells (APCs) and their activation prompts the …
DCs are the most potent antigen presenting cells (APCs) and their activation prompts the …
Construction and characterization of virus-like particles: a review
A Zeltins - Molecular biotechnology, 2013 - Springer
Over the last three decades, virus-like particles (VLPs) have evolved to become a widely
accepted technology, especially in the field of vaccinology. In fact, some VLP-based …
accepted technology, especially in the field of vaccinology. In fact, some VLP-based …
Thirty years of baculovirus–insect cell protein expression: from dark horse to mainstream technology
MM Van Oers, GP Pijlman… - Journal of General …, 2015 - microbiologyresearch.org
In December 1983, a seminal paper appeared on the overexpression of human IFN-β in
insect cells with a genetically engineered baculovirus. The finding that baculoviruses …
insect cells with a genetically engineered baculovirus. The finding that baculoviruses …
COVID‐19 in early 2023: Structure, replication mechanism, variants of SARS‐CoV‐2, diagnostic tests, and vaccine & drug development studies
Abstract Coronavirus Disease‐19 (COVID‐19) is an infectious disease caused by severe
acute respiratory syndrome‐coronaviruses‐2 (SARS‐CoV‐2), a highly pathogenic and …
acute respiratory syndrome‐coronaviruses‐2 (SARS‐CoV‐2), a highly pathogenic and …
Virus-like particles as preventive and therapeutic cancer vaccines
Virus-like particles (VLPs) are self-assembled viral protein complexes that mimic the native
virus structure without being infectious. VLPs, similarly to wild type viruses, are able to …
virus structure without being infectious. VLPs, similarly to wild type viruses, are able to …
Virus-like particles as nanocarriers for intracellular delivery of biomolecules and compounds
J He, L Yu, X Lin, X Liu, Y Zhang, F Yang, W Deng - Viruses, 2022 - mdpi.com
Virus-like particles (VLPs) are nanostructures assemble from viral proteins. Besides widely
used for vaccine development, VLPs have also been explored as nanocarriers for cargo …
used for vaccine development, VLPs have also been explored as nanocarriers for cargo …