[HTML][HTML] Oral cancer in young adults: incidence, risk factors, prognosis, and molecular biomarkers

D Lenoci, E Moresco, S Cavalieri… - Frontiers in …, 2024 - pmc.ncbi.nlm.nih.gov
Oral cavity squamous cell carcinoma (OCSCC) predominantly affects the tongue and the
floor of the mouth, primarily in patients over 50 years of age. Incidence and mortality rates …

Current trends in precision medicine and next-generation sequencing in head and neck cancer

RN Solis, DA Silverman, AC Birkeland - Current treatment options in …, 2022 - Springer
Opinion statement As the field of oncology enters the era of precision medicine and targeted
therapies, we have come to realize that there may be no single “magic bullet” for patients …

Prognostic impact of lymphovascular and perineural invasion in squamous cell carcinoma of the tongue

Q Huang, Y Huang, C Chen, Y Zhang, J Zhou, C Xie… - Scientific reports, 2023 - nature.com
This study aimed to investigate the prognostic impact of lymphovascular and perineural
invasions in patients with squamous cell carcinoma of the tongue who received surgery …

Trends in Oral Tongue Cancer Incidence in the US

T Burus, H Damgacioglu, B Huang… - … –Head & Neck …, 2024 - jamanetwork.com
Importance Oral tongue cancer (OTC) incidence has increased rapidly among young (< 50
years) non-Hispanic White individuals in the US during the past 2 decades; however, it is …

Shifting Epidemiology Trends in Tongue Cancer: A Retrospective Cohort Study

Y Sakr, O Hamdy, M Eldeghedi, R Abdelaziz… - Cancers, 2023 - mdpi.com
Simple Summary Tongue cancer typically has male predominance. However, several
studies have documented an increasing number of incidences among the younger …

The prognostic role of sex and hemoglobin levels in patients with oral tongue squamous cell carcinoma

M Tagliabue, O D'Ecclesiis, R De Berardinis… - Frontiers in …, 2022 - frontiersin.org
Background Women and men differ genetically, biologically (sex) and by social construct
(gender), possibly impacting on prognostic factors in predicting cancer survival. Hemoglobin …

WEE1 kinase inhibitor MK‐1775 sensitizes oral tongue squamous cell carcinoma cells to radiation irrespective of TP53 status

AH Al‐Jamaei, JGAM de Visscher… - Oral …, 2023 - Wiley Online Library
Objective Oral tongue squamous cell carcinoma (OTSCC) frequently harbors non‐functional
p53 and depends on G2/M checkpoint mediated by WEE1. WEE1 suppression has been …

Contrasting clinical outcomes and socio‐economic impact of young versus elderly‐onset oral squamous cell carcinoma, a novel health economic analysis

M Singh, K Thankappan, D Balasubramanian… - Cancer …, 2024 - Wiley Online Library
Objectives The incidence of young‐onset oral squamous cell carcinoma (OSCC) is growing,
even among non‐smokers/drinkers. The effects of adverse histopathological features on …

Il17Rb expression is associated with malignant cancer behaviors and poor prognosis in oral cancer

SSF Yuan, CW Su, LP Chan, HDH Nguyen… - Oral …, 2024 - Wiley Online Library
Objectives Previously, we demonstrated that IL17RB plays an essential role in lung cancer
progression. This study aimed to determine whether IL17RB correlates with oral cancer and …

[HTML][HTML] Oral tongue carcinoma: prognostic changes according to the updated 2020 version of the AJCC/UICC TNM staging system

M Tagliabue, R De Berardinis, P Belloni… - Acta …, 2022 - ncbi.nlm.nih.gov
Background This study aimed to evaluate the performance of the 2017 8 th TNM edition and
the latest update in 2020 compared to the 7 th in a large cohort of patients affected by oral …