Rejection of the kidney allograft
BJ Nankivell, SI Alexander - New England Journal of Medicine, 2010 - Mass Medical Soc
Rejection of the Kidney Allograft | NEJM Skip to main content NEJM Group Follow Us Facebook
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Effector mechanisms of rejection
A Moreau, E Varey, I Anegon… - Cold Spring …, 2013 - perspectivesinmedicine.cshlp.org
Organ transplantation appears today to be the best alternative to replace the loss of vital
organs induced by various diseases. Transplants can, however, also be rejected by the …
organs induced by various diseases. Transplants can, however, also be rejected by the …
Biomarkers for kidney transplant rejection
DJ Lo, B Kaplan, AD Kirk - Nature Reviews Nephrology, 2014 - nature.com
The immune management of organ transplant recipients is imperfect. Beyond general
dosing guidelines for immunosuppressive agents and clinical diagnostic tests for rejection or …
dosing guidelines for immunosuppressive agents and clinical diagnostic tests for rejection or …
Urinary cXC motif chemokine 10 independently improves the noninvasive diagnosis of antibody–mediated kidney allograft rejection
M Rabant, L Amrouche, X Lebreton… - Journal of the …, 2015 - journals.lww.com
Urinary levels of CXC motif chemokine 9 (CXCL9) and CXCL10 can noninvasively diagnose
T cell–mediated rejection (TCMR) of renal allografts. However, performance of these …
T cell–mediated rejection (TCMR) of renal allografts. However, performance of these …
[HTML][HTML] Urinary chemokines CXCL9 and CXCL10 are noninvasive markers of renal allograft rejection and BK viral infection
JA Jackson, EJ Kim, B Begley, J Cheeseman… - American Journal of …, 2011 - Elsevier
Renal transplant recipients require periodic surveillance for immune-based complications
such as rejection and infection. Noninvasive monitoring methods are preferred, particularly …
such as rejection and infection. Noninvasive monitoring methods are preferred, particularly …
[HTML][HTML] Gene expression in biopsies of acute rejection and interstitial fibrosis/tubular atrophy reveals highly shared mechanisms that correlate with worse long‐term …
Interstitial fibrosis and tubular atrophy (IFTA) is found in approximately 25% of 1‐year
biopsies posttransplant. It is known that IFTA correlates with decreased graft survival when …
biopsies posttransplant. It is known that IFTA correlates with decreased graft survival when …
[HTML][HTML] Development and validation of an optimized integrative model using urinary chemokines for noninvasive diagnosis of acute allograft rejection
C Tinel, A Devresse, A Vermorel, V Sauvaget… - American Journal of …, 2020 - Elsevier
The urinary chemokines CXCL9 and CXCL10 are promising noninvasive diagnostic
markers of acute rejection (AR) in kidney recipients, but their levels might be confounded by …
markers of acute rejection (AR) in kidney recipients, but their levels might be confounded by …
Establishing biomarkers in transplant medicine: a critical review of current approaches
Although the management of kidney transplant recipients has greatly improved over recent
decades, the assessment of individual risks remains highly imperfect. Individualized …
decades, the assessment of individual risks remains highly imperfect. Individualized …
[HTML][HTML] Validity and utility of urinary CXCL10/Cr immune monitoring in pediatric kidney transplant recipients
TD Blydt-Hansen, A Sharma, IW Gibson… - American Journal of …, 2021 - Elsevier
Individualized posttransplant immunosuppression is hampered by suboptimal monitoring
strategies. To validate the utility of urinary CXCL10/Cr immune monitoring in children, we …
strategies. To validate the utility of urinary CXCL10/Cr immune monitoring in children, we …
[HTML][HTML] Role of chemokine (C–X–C motif) ligand 10 (CXCL10) in renal diseases
J Gao, L Wu, S Wang, X Chen - Mediators of Inflammation, 2020 - hindawi.com
Chemokine C–X–C ligand 10 (CXCL10), also known as interferon-γ-inducible protein 10 (IP-
10), exerts biological function mainly through binding to its specific receptor, CXCR3 …
10), exerts biological function mainly through binding to its specific receptor, CXCR3 …