Rural communities in developing countries lack access to affordable, reliable, and
sustainable forms of energy, which are essential factors for improving living conditions …

Fine-tuning cellular physiology in response to intracellular and environmental cues requires
precise temporal and spatial control of gene expression. High-resolution imaging …

The 70-kDa heat shock proteins (Hsp70s) are ubiquitous molecular chaperones that act in a
large variety of cellular protein folding and remodelling processes. They function virtually at …

This perspective is partly review and partly proposal. N-degrons and C-degrons are
degradation signals whose main determinants are, respectively, the N-terminal and C …

Codon usage bias, the preference for certain synonymous codons, is found in all genomes.
Although synonymous mutations were previously thought to be silent, a large body of …

The genetic code is degenerate, and most amino acids are encoded by two to six
synonymous codons. Codon usage bias, the preference for certain synonymous codons, is a …

As our understanding of the cell interior has grown, we have come to appreciate that most
cellular operations are localized, that is, they occur at discrete and identifiable locations or …

Liquid-like condensates have been thought to be sphere-like. Recently, various
condensates with filamentous morphology have been observed in cells. One such …

Local translation allows spatial control of gene expression. Here, we performed a dual
protein-mRNA localization screen, using smFISH on 523 human cell lines expressing GFP …

INTRODUCTION Most newly synthesized proteins associate into macromolecular
complexes to become functional. Complex formation requires that subunits find each other …