Pain associated with mechanical, chemical, and thermal heat stimulation of the ocular
surface is mediated by trigeminal ganglion neurons, while cold thermoreceptors detect …

Neurotrophic Keratopathy (NK) refers to a condition where corneal epitheliopathy leading to
frank epithelial defect with or without stromal ulceration (melting) is associated with reduced …

One of the most compelling features of dry eye disease (DED) is that it occurs more
frequently in women than men. In fact, the female sex is a significant risk factor for the …

In vivo confocal microscopy (IVCM) is becoming an indispensable tool for studying corneal
physiology and disease. Enabling the dissection of corneal architecture at a cellular level …

Dry eye has gained recognition as a public health problem given its prevalence, morbidity,
and cost implications. Dry eye can have a variety of symptoms including blurred vision …

Eye pain is an unpleasant sensory and emotional experience including sensory-
discriminative, emotional, cognitive, and behavioral components and supported by distinct …

Neuropathic pain is caused by a primary lesion or dysfunction of the nervous system and
can occur in the cornea. However, neuropathic corneal pain (NCP) is currently an ill-defined …

Objective Patients suffering from corneal neuropathy may present with photoallodynia; ie,
increased light sensitivity, frequently with a normal slit-lamp examination. This study aimed …

This paper outlines changes to the ocular surface caused by contact lenses and their degree
of clinical significance. Substantial research and development to improve oxygen …

Objective Corneal nerve damage may result in neuropathic corneal pain (NCP). Autologous
serum tears (AST) have been shown to results in nerve regeneration and may help alleviate …