Abstract Chalcone [(E)-1, 3-diphenyl-2-propene-1-one], a small molecule with α, β
unsaturated carbonyl group is a precursor or component of many natural flavonoids and …

Neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD),
and Huntington's disease (HD), are characterized by the progressive degeneration of …

Background Amyloid aggregate deposition is the key feature of Alzheimer's disease. The
proteinaceous aggregates found in the afflicted brain are the intra-neuronal neurofibrillary …

Aging reduces homeostasis and contributes to increasing the risk of brain diseases and
death. Some of the principal characteristics are chronic and low-grade inflammation, a …

Plant roots, due to a high content of natural antioxidants for many years, have been used in
herbal medicine. It has been documented that the extract of Baikal skullcap (Scutellaria …

Alzheimer's disease (AD) is a neurodegenerative disease that leads to progressive loss of
memory and dementia. The pathological hallmarks of AD include extracellular accumulation …

Several studies have reported neuroprotective effects by natural products. A wide range of
natural compounds have been investigated, and some of these may play a beneficial role in …

Attempts to develop a disease modifying intervention for Alzheimer's disease (AD) through
targeting amyloid β (Aβ) have so far been unsuccessful. There is, therefore, a need for novel …

Alzheimer's disease is a progressive neurodegenerative disease characterized by the
presence of amyloid-β plaques in the extracellular environment and aggregates of Tau …

Finding an effective therapeutic to prevent or cure AD has been difficult due to the
complexity of the brain and limited experimental models. This study utilized unmodified and …