Ocular neurodegenerative diseases: interconnection between retina and cortical areas
The possible interconnection between the eye and central nervous system (CNS) has been
a topic of discussion for several years just based on fact that the eye is properly considered …
a topic of discussion for several years just based on fact that the eye is properly considered …
Medical therapy for glaucoma: A review
RJ Casson - Clinical & Experimental Ophthalmology, 2022 - Wiley Online Library
A number of pharmacological targets are exploited to modify the parameters in the
Goldmann equation and reduce the intraocular pressure (IOP). This strategy constitutes the …
Goldmann equation and reduce the intraocular pressure (IOP). This strategy constitutes the …
[HTML][HTML] Testing drug release from medicated contact lenses: The missing link to predict in vivo performance
Contact lenses (CLs) offer a wide variety of advantages as ocular drug-releasing platforms,
but the feasibility of medicated CL development is constrained by numerous scientific …
but the feasibility of medicated CL development is constrained by numerous scientific …
Intravitreal injectable hydrogels for sustained drug delivery in glaucoma treatment and therapy
Glaucoma is extensively treated with topical eye drops containing drugs. However, the
retention time of the loaded drugs and the in vivo bioavailability of the drugs are highly …
retention time of the loaded drugs and the in vivo bioavailability of the drugs are highly …
Looking into the future: Gene and cell therapies for glaucoma
AM Komáromy, KL Koehl, SA Park - Veterinary ophthalmology, 2021 - Wiley Online Library
Glaucoma is a complex group of optic neuropathies that affects both humans and animals.
Intraocular pressure (IOP) elevation is a major risk factor that results in the loss of retinal …
Intraocular pressure (IOP) elevation is a major risk factor that results in the loss of retinal …
[HTML][HTML] Glaucoma: Novel antifibrotic therapeutics for the trabecular meshwork
M Qin, C Yu-Wai-Man - European Journal of Pharmacology, 2023 - Elsevier
Glaucoma is a chronic and progressive neurodegenerative disease characterized by the
loss of retinal ganglion cells and visual field defects, currently affecting around 1% of the …
loss of retinal ganglion cells and visual field defects, currently affecting around 1% of the …
Intracameral drug delivery: a review of agents, indications, and outcomes
M Gautam, R Gupta, P Singh, V Verma… - Journal of Ocular …, 2023 - liebertpub.com
An intracameral (IC) injection directly delivers the drug into the anterior chamber of the eye.
This targeted drug delivery technique overcomes the ocular barriers and offers a high …
This targeted drug delivery technique overcomes the ocular barriers and offers a high …
[HTML][HTML] Progress in drug formulation design and delivery of medicinal substances used in ophthalmology
KB Wroblewska, B Jadach… - International Journal of …, 2021 - Elsevier
Due to the very low bioavailability of drugs administered to the surface of the eyeball, issues
related to the formulation of an ophthalmic drug pose a technological challenge. The …
related to the formulation of an ophthalmic drug pose a technological challenge. The …
3D-printed long-acting 5-fluorouracil implant to prevent conjunctival fibrosis in glaucoma
N Ioannou, J Luo, M Qin, M Di Luca… - Journal of Pharmacy …, 2023 - academic.oup.com
Objectives To develop a sustained release 5-fluorouracil (5-FU) implant by three-
dimensional (3D) printing to effectively prevent conjunctival fibrosis after glaucoma surgery …
dimensional (3D) printing to effectively prevent conjunctival fibrosis after glaucoma surgery …
[HTML][HTML] Drug Delivery Systems for Glaucoma: A Narrative Review
AM Fea, V Vallino, M Cossu, V Marica, C Novarese… - Pharmaceuticals, 2024 - mdpi.com
Glaucoma is one of the world's leading causes of blindness, and its management is
challenging. The main objective is to lower intraocular pressure through medical, para …
challenging. The main objective is to lower intraocular pressure through medical, para …