The impact of Foxp3+ regulatory T‐cells on CD8+ T‐cell dysfunction in tumour microenvironments and responses to immune checkpoint inhibitors
M Attias, CA Piccirillo - British Journal of Pharmacology, 2024 - Wiley Online Library
Immune checkpoint inhibitors (ICIs) have been a breakthrough in cancer therapy, inducing
durable remissions in responding patients. However, they are associated with variable …
durable remissions in responding patients. However, they are associated with variable …
Deciphering the developmental trajectory of tissue-resident Foxp3+ regulatory T cells
F Alvarez, Z Liu, A Bay, CA Piccirillo - Frontiers in Immunology, 2024 - frontiersin.org
Foxp3+ TREG cells have been at the focus of intense investigation for their recognized roles
in preventing autoimmunity, facilitating tissue recuperation following injury, and …
in preventing autoimmunity, facilitating tissue recuperation following injury, and …
Suppressed transcript diversity and immune response in COVID-19 ICU patients: a longitudinal study
Understanding the dynamic changes in gene expression during Acute Respiratory Distress
Syndrome (ARDS) progression in post-acute infection patients is crucial for unraveling the …
Syndrome (ARDS) progression in post-acute infection patients is crucial for unraveling the …
Stability and plasticity of regulatory T cells in health and disease
E Contreras-Castillo, VY García-Rasilla… - Journal of Leukocyte …, 2024 - academic.oup.com
The mechanisms that negatively regulate inflammation upon a pathogenic stimulus are
crucial for the maintenance of tissue integrity and organ function. T regulatory cells are one …
crucial for the maintenance of tissue integrity and organ function. T regulatory cells are one …
Investigating the Epigenetic Landscape of the Ifng Locus During Proinflammatory Regulatory T Cell Reprogramming
VZ Jiao - 2024 - search.proquest.com
Regulatory T (Treg) cells are distinguished by the expression of the master transcription
factor forkhead box P3 (Foxp3), which plays a pivotal role in facilitating their …
factor forkhead box P3 (Foxp3), which plays a pivotal role in facilitating their …
O polimorfismo rs187238 no gene da Interleucina-18 está associado a alterações nas Lipoproteínas de alta densidade em pacientes ambulatoriais com COVID-19
GA Viana - 2024 - repositorio.ufc.br
Covid-19 is an infectious respiratory disease characterized by the excessive production of
proinflammatory cytokines, which has led to disorders of multiple organs and systems, with …
proinflammatory cytokines, which has led to disorders of multiple organs and systems, with …