Abstract (Pro) renin receptor (PRR), along with its soluble form, sPRR, functions not only as
a crucial activator of the local renin-angiotensin system but also engages with and activates …

The (pro) renin receptor (PRR) is a single-transmembrane protein that regulates the local
renin-angiotensin system and participates in various intracellular signaling pathways, thus …

It is well demonstrated that activation of renal PRR ([pro] renin receptor) contributes to AngII
(angiotensin II)-induced hypertension. Relatively, less is known for the function of sPRR …

FURIN is a pro-protein convertase previously shown to be important for placental
syncytialisation (Zhou et al.), a process of cell fusion whereby placental cytotrophoblast cells …

Objective The proprotein convertase furin is known to be involved in the processing of pro-B-
type natriuretic peptide (proBNP) and prorenin receptor (PRR), suggesting that it has a …

Placental renin-angiotensin system (RAS) components; prorenin, angiotensinogen, and
angiotensin (Ang) II type 1 receptor (AT 1 R) are upregulated during syncytialisation. This …

Preeclampsia is classified as new-onset hypertension coupled with gross endothelial
dysfunction. Placental (pro) renin receptor ((P) RR) and plasma soluble (P) RR (s (P) RR) …

In preeclamptic pregnancies, which are characterised by maternal hypertension and
impaired placental development and function, we propose that there is enhanced secretion …

The (pro) renin receptor ((P) RR) is an essential component of the renin–angiotensin system
(RAS) as a specific single-pass transmembrane receptor for prorenin and renin and has now …

Abstract The (pro) renin receptor ((P) RR) is a multi-functional protein that can be
proteolytically cleaved and released in a soluble form (s (P) RR). Recently, the (P) RR and s …