Protective effects of melatonin against the toxic effects of environmental pollutants and heavy metals on testicular tissue: A systematic review and meta-analysis of …

N Dehdari Ebrahimi, S Parsa, F Nozari… - Frontiers in …, 2023 - frontiersin.org
Background Environmental pollution and infertility are two modern global challenges that
agonize personal and public health. The causal relationship between these two deserves …

The roles of the circadian hormone melatonin in drug addiction

S Jia, X Guo, Z Chen, S Li, X Liu - Pharmacological Research, 2022 - Elsevier
Given the devastating social and health consequences of drug addiction and the limitations
of current treatments, a new strategy is needed. Circadian system disruptions are frequently …

Melatonin promotes male reproductive performance and increases testosterone synthesis in mammalian Leydig cells

M Yang, S Guan, J Tao, K Zhu, D Lv… - Biology of …, 2021 - academic.oup.com
Leydig cells play a critical role in male reproductive physiology, and their dysfunction is
usually associated with male infertility. Melatonin has an important protective and regulatory …

Deterioration of semen quality and sperm‐DNA integrity as influenced by cigarette smoking in fertile and infertile human male smokers—A prospective study

P Ranganathan, KA Rao… - Journal of cellular …, 2019 - Wiley Online Library
In modernized lifestyle smoking is one of the trendy, psychological, and socioeconomic
scenarios of young adolescents mainly in the age of the reproductive stage. Based on a …

Melatonin inhibits apoptosis and oxidative stress of mouse Leydig cells via a SIRT1-dependent mechanism

G Xu, J Zhao, H Liu, J Wang, W Lu - Molecules, 2019 - mdpi.com
The purpose of the present study is to examine the effects of melatonin on apoptosis and
oxidative stress in mouse Leydig cells and to elucidate the mechanisms responsible for …

Ginseng alleviates folliculogenesis disorders via induction of cell proliferation and downregulation of apoptotic markers in nicotine-treated mice

M Faghani, S Saedi, K Khanaki… - Journal of Ovarian …, 2022 - Springer
Background Ginseng is a powerful phytoestrogen with high antioxidant properties. Objective
This study aimed to evaluate the effect of Panax Ginseng (PG) on folliculogenesis …

Histopathological analysis of testis: Effects of astaxanthin treatment against nicotine toxicity

B Sobhani, S Roomiani, Z Ahmadi… - Iranian journal of …, 2019 - ijt.arakmu.ac.ir
Background: Nicotine is a toxic compound in the cigarette smoke and has destructive effects
on various human organs. Astaxanthin is a carotenoid with high antioxidant property. In this …

Coenzyme Q10 mitigates ionizing radiation-induced testicular damage in rats through inhibition of oxidative stress and mitochondria-mediated apoptotic cell death

RS Said, HA Mohamed, MM Kamal - Toxicology and Applied Pharmacology, 2019 - Elsevier
Radiotherapy is a common treatment modality for cancer patients; however, its use is limited
by decreasing the probability of fertility in male cancer survivors. Therefore, this study aimed …

Effect of Astaxanthin Treatment on the Sperm Quality of the Mice Treated with Nicotine.

M Ashrafizadeh, Z Ahmadi - Reviews in Clinical Medicine, 2019 - search.ebscohost.com
Introduction: Today, smoking has become a common habit, and researchers have largely
been concerned with the adverse health effects of smoking. Some approaches have been …

[HTML][HTML] Exposure to nicotine regulates prostaglandin E2 secretion and autophagy of granulosa cells to retard follicular maturation in mammals

X Zhou, Y He, H Quan, J Yang, S Li, Y Jiang, J Li… - Ecotoxicology and …, 2024 - Elsevier
Exposure to nicotine by cigarette smoking have shown strongly defectives on the
physiological function of ovaries, which in turn leads to disorders of fertility in women …