Engineered exosomes from different sources for cancer-targeted therapy

M Zhang, S Hu, L Liu, P Dang, Y Liu, Z Sun… - Signal transduction and …, 2023 - nature.com
Exosome is a subgroup of extracellular vesicles, which has been serving as an efficient
therapeutic tool for various diseases. Engineered exosomes are the sort of exosomes …

[HTML][HTML] Stimuli-responsive nanocarriers for drug delivery, tumor imaging, therapy and theranostics

P Mi - Theranostics, 2020 - ncbi.nlm.nih.gov
In recent years, much progress has been motivated in stimuli-responsive nanocarriers,
which could response to the intrinsic physicochemical and pathological factors in diseased …

Gene-engineered exosomes-thermosensitive liposomes hybrid nanovesicles by the blockade of CD47 signal for combined photothermal therapy and cancer …

L Cheng, X Zhang, J Tang, Q Lv, J Liu - Biomaterials, 2021 - Elsevier
CD47, overexpressed on kinds of tumor cells, activates a “don't eat me” signal through
binding to signal regulatory protein α (SIRPα), leading to immune escape from the …

Advances in biomaterials for drug delivery

OS Fenton, KN Olafson, PS Pillai… - Advanced …, 2018 - Wiley Online Library
Advances in biomaterials for drug delivery are enabling significant progress in biology and
medicine. Multidisciplinary collaborations between physical scientists, engineers, biologists …

Wireless on-demand drug delivery

SM Mirvakili, R Langer - Nature Electronics, 2021 - nature.com
Wireless on-demand drug delivery systems exploit exogenous stimuli—acoustic waves,
electric fields, magnetic fields and electromagnetic radiation—to trigger drug carriers. The …

Bioresponsive materials

Y Lu, AA Aimetti, R Langer, Z Gu - Nature Reviews Materials, 2016 - nature.com
Abstract 'Smart'bioresponsive materials that are sensitive to biological signals or to
pathological abnormalities, and interact with or are actuated by them, are appealing …

Nanocarrier cancer therapeutics with functional stimuli-responsive mechanisms

N Kaushik, SB Borkar, SK Nandanwar… - Journal of …, 2022 - Springer
Presently, nanocarriers (NCs) have gained huge attention for their structural ability, good
biocompatibility, and biodegradability. The development of effective NCs with stimuli …

Transformable liquid-metal nanomedicine

Y Lu, Q Hu, Y Lin, DB Pacardo, C Wang, W Sun… - Nature …, 2015 - nature.com
To date, numerous inorganic nanocarriers have been explored for drug delivery systems
(DDSs). However, the clinical application of inorganic formulations has often been hindered …

External triggering and triggered targeting strategies for drug delivery

Y Wang, DS Kohane - Nature Reviews Materials, 2017 - nature.com
Drug delivery systems that are externally triggered to release drugs and/or target tissues
hold considerable promise for improving the treatment of many diseases by minimizing …

[HTML][HTML] Wireless optofluidic systems for programmable in vivo pharmacology and optogenetics

JW Jeong, JG McCall, G Shin, Y Zhang, R Al-Hasani… - Cell, 2015 - cell.com
In vivo pharmacology and optogenetics hold tremendous promise for dissection of neural
circuits, cellular signaling, and manipulating neurophysiological systems in awake …