[HTML][HTML] Nerves in gastrointestinal cancer: from mechanism to modulations

N Vaes, M Idris, W Boesmans, MM Alves… - Nature Reviews …, 2022 - nature.com
Maintenance of gastrointestinal health is challenging as it requires balancing multifaceted
processes within the highly complex and dynamic ecosystem of the gastrointestinal tract …

Role of the tumor microenvironment in cancer hallmarks and targeted therapy

R Naser, I Fakhoury, A El-Fouani… - International …, 2022 - spandidos-publications.com
Genetic alterations drive tumor onset and progression. However, the cross-talk between
tumor cells and the benign components of the surrounding stroma can also promote the …

Ferredoxin 1 is a cuproptosis-key gene responsible for tumor immunity and drug sensitivity: A pan-cancer analysis

L Yang, Y Zhang, Y Wang, P Jiang, F Liu… - Frontiers in …, 2022 - frontiersin.org
Ferredoxin 1 (FDX1) functions by transferring electrons from NADPH to mitochondrial
cytochrome P450 via the ferredoxin reductase and is the key regulator in copper-dependent …

Cancer plasticity: investigating the causes for this agility

S Saha, N Pradhan, B Neha, R Mahadevappa… - Seminars in cancer …, 2023 - Elsevier
Cancer is not a hard-wired phenomenon but an evolutionary disease. From the onset of
carcinogenesis, cancer cells continuously adapt and evolve to satiate their ever-growing …

Iron metabolism in colorectal cancer: A balancing act

D Estêvão, M da Cruz-Ribeiro, AP Cardoso, ÂM Costa… - Cellular Oncology, 2023 - Springer
Background Colorectal cancer (CRC) is the third most commonly diagnosed cancer and the
second deadliest malignancy worldwide. Current dietary habits are associated with …

[HTML][HTML] Investigation of high frequency irreversible electroporation for Canine spontaneous primary lung tumor ablation

AN Hay, KN Aycock, MF Lorenzo, K David… - …, 2024 - pmc.ncbi.nlm.nih.gov
In this study, the feasibility of treating canine primary lung tumors with high-frequency
irreversible electroporation (H-FIRE) was investigated as a novel lung cancer treatment …

[HTML][HTML] Bridging the gap between clear cell renal cell carcinoma and cutaneous melanoma: the role of SCARB1 in dysregulated cholesterol metabolism

L Song, S Wang, X Zhang, N Song, Y Lu… - Aging (Albany NY …, 2023 - ncbi.nlm.nih.gov
Objective: The metabolism of cholesterol has been found to be closely related to the
proliferation, invasion, and metastasis of tumors. The purpose of this study was to investigate …

Leveraging diverse cell-death patterns to predict the prognosis, immunotherapy and drug sensitivity of clear cell renal cell carcinoma

X Zhang, M Zhang, L Song, S Wang, X Wei, W Shao… - Scientific Reports, 2023 - nature.com
Clear cell renal cell carcinoma (ccRCC) poses clinical challenges due to its varied
prognosis, tumor microenvironment attributes, and responses to immunotherapy. We …

[HTML][HTML] Experimental validation and pan-cancer analysis identified COL10A1 as a novel oncogene and potential therapeutic target in prostate cancer

S Xu, D Liu, Z Qin, Z Liang, H Xie, B Yi, K Wang… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Background: Type X collagen (COL10) is a homologous trimeric non-fibrillar collagen found
in the extracellular matrix of human tissues, and it exhibits a distinctive white appearance …

Construction of a prognostic 6-gene signature for breast cancer based on multi-omics and single-cell data

Z Xing, D Lin, Y Hong, Z Ma, H Jiang, Y Lu… - Frontiers in …, 2023 - frontiersin.org
Background Breast cancer (BC) is one of the females' most common malignant tumors there
are large individual differences in its prognosis. We intended to uncover novel useful genetic …