Over the last years, the pharmaceutical industry has faced real challenges regarding quality
assurance. In this context, the establishment of more holistic approaches to the …

Thermal processing has gained much interest in the pharmaceutical industry, particularly for
the enhancement of solubility, bioavailability, and dissolution of active pharmaceutical …

Scientific regulatory systems with suitable analytical methods for monitoring quality, safety,
and efficacy are essential in medicinal plant drug discovery. There have been only few …

In the last few decades, hot-melt extrusion (HME) has emerged as a rapidly growing
technology in the pharmaceutical industry, due to its various advantages over other …

Vonoprazan fumarate (VPZ), a potent potassium-competitive acid blocker, holds great
promise as a therapeutic option for addressing acid-related disorders. This study introduces …

Background Hot-melt extrusion (HME) significantly affects pharmaceutical manufacturing by
enhancing drug solubility and bioavailability. Advancements in HME technology to produce …

The pharmaceutical industry has embraced the quality-by-design (QbD) approach as a
promising development, formulation and manufacturing strategy. QbD provides a systematic …

The aim of our study was to adapt the analytical quality by design (AQbD) approach to
design an effective in vitro release test method using USP apparatus IV with a semi-solid …

The poor solubility of a large number of active pharmaceutical ingredients (APIs) is a major
challenge in pharmaceutical research. Therefore, the extrusion of amorphous solid …

Serratiopeptidase (SRP) is a proteolytic enzyme that emerged as one of the most potent anti‐
inflammatory and analgesic drugs. The purpose of the present study was to formulate and …