Nanomaterials (NM) arouse interest in various fields of science and industry due to their
composition-tunable properties and the ease of modification. They appear currently as …

Abstract Interleukin-8 (IL-8) is a proinflammatory CXC chemokine associated with the
promotion of neutrophil chemotaxis and degranulation. This chemokine activates multiple …

What are nanoparticles and why are they important in dermatology? These questions are
addressed by highlighting recent developments in the nanotechnology field that have …

Melanoma derived from melanocytes is the most aggressive genre of skin cancer. Although
the considerable advancement in the study of human cancer biology and drug discovery …

The drug efflux transporter ABCB5 identifies cancer stem–like cells (CSC) in diverse human
malignancies, where its expression is associated with clinical disease progression and …

Highly metastatic and chemotherapy-resistant properties of malignant melanomas stand as
challenging barriers to successful treatment; yet, the mechanisms responsible for their …

Metastatic melanoma remains a lethal disease with a long-term remission rate of less than
10%. Despite many years of research, there has not been a new drug approved in this …

Cytokines are known to play pivotal roles in cancer initiation, progression and pathogenesis.
Accumulating evidences suggest differences in basal and stress-induced cytokine profiles of …

Background More than half of patients with melanoma that has spread to regional lymph
nodes develop recurrent disease within the first 3 years after surgery. The aim of the study …

Background BRAF and MEK inhibitors have demonstrated significant survival benefits for
patients with cutaneous melanoma. However, their use for uveal melanoma (UM) is less …