Simple Summary For mammalian cells, glucose is a major source of energy. In the presence
of oxygen, a complete breakdown of glucose generates 36 molecules of ATP from one …

The primary metabolic substrate for cells is glucose, which acts as both a source of energy
and a substrate in several processes. However, being lipophilic, the cell membrane is …

Microglia continuously survey the brain parenchyma and actively shift status following
stimulation. These processes demand a unique bioenergetic programme; however, little is …

Colorectal cancer (CRC) is the third leading cause of death in men and the fourth in women
worldwide and is characterized by deranged cellular energetics. Thymoquinone, an active …

Glycolysis contributes to cell metabolism and facilitates cell proliferation of oral squamous
cell carcinoma (OSCC), the most common type of oral cancer. Understanding the regulatory …

The most frequent mutated oncogene family in the history of human cancer is the RAS gene
family, including NRAS, HRAS, and, most importantly, KRAS. A hallmark of pancreatic …

Aerobic glycolysis (Warburg effect), a hallmark of cancer, plays a critical role in cancer cell
growth and metastasis; however, direct inhibition of the Warburg effect remains largely …

The rewiring of cellular metabolism is a defining characteristic of cancer, as tumor cells
adapt to acquire essential nutrients from a nutrient-poor environment to sustain their viability …

Ovarian cancer is one of the most lethal cancers in female reproductive system due to
heterogeneity and lack of effective treatment. Targeting aerobic glycolysis, a predominant …

Simple Summary Glycolysis is one of the hallmarks of cancer. Therefore, the development of
novel therapeutical strategies for colorectal cancer targeting glycolysis may improve …