Male infertility

ML Eisenberg, SC Esteves, DJ Lamb… - Nature Reviews …, 2023 - nature.com
Clinical infertility is the inability of a couple to conceive after 12 months of trying. Male factors
are estimated to contribute to 30–50% of cases of infertility. Infertility or reduced fertility can …

Improved phenotypic classification of male infertility to promote discovery of genetic causes

MJ Wyrwoll, GW van der Heijden, C Krausz… - Nature Reviews …, 2024 - nature.com
An increasing number of genes are being described in the context of non-syndromic male
infertility. Linking the underlying genetic causes of non-syndromic male infertility with clinical …

Improving standard practices in studies using results from basic human semen examination

L Björndahl, SC Esteves, A Ferlin, N Jørgensen… - …, 2023 - Wiley Online Library
The purpose of this article is to provide an explanation of the background behind a checklist
that declares the laboratory methods used in a scientific study. It focuses primarily on …

Evaluation of sperm DNA fragmentation using two different methods: TUNEL via fluorescence microscopy, and flow cytometry

K Chatzimeletiou, A Fleva, TT Nikolopoulos… - Medicina, 2023 - mdpi.com
Background and Objectives: Sperm DNA fragmentation refers to any break in one or both of
the strands of DNA in the head of a sperm. The most widely used methodologies for …

Immune regulatory cytokines in seminal plasma of healthy men: A scoping review and analysis of variance

HE Lyons, BM Arman, SA Robertson, DJ Sharkey - Andrology, 2023 - Wiley Online Library
Objective Seminal plasma cytokines are associated with fertility and reproductive health, but
progressing their clinical utility is hampered by absence of reference data on concentration …

Influence of substance use on male reproductive health and offspring outcomes

JO Lo, JC Hedges, WH Chou, KR Tager… - Nature Reviews …, 2024 - nature.com
The prevalence of substance use globally is rising and is highest among men of
reproductive age. In Africa, and South and Central America, cannabis use disorder is most …

[PDF][PDF] EAU Guidelines

A Salonia, C Bettocchi, P Capogrosso… - The EAU Annual …, 2023 - medamorhealth.com
EAU Guidelines on Page 1 A. Salonia (Chair), C. Bettocchi, P. Capogrosso, J. Carvalho, G.
Corona, G. Hatzichristodoulou, TH Jones, A. Kadioglu, JI Martinez-Salamanca,S. Minhas (Vice-chair) …

Mechanistic screening of reproductive toxicity in a novel 3D testicular co-culture model shows significant impairments following exposure to low-dibutyl phthalate …

R Almamoun, P Pierozan, O Karlsson - Archives of Toxicology, 2024 - Springer
To improve the mechanistic screening of reproductive toxicants in chemical-risk assessment
and drug development, we have developed a three-dimensional (3D) heterogenous …

Sperm Concentration Improvement May Be a Parameter Predicting Efficacy of FSH Therapy of Male Idiopathic Infertility

D Santi, G Spaggiari, L Dalla Valentina, M Romeo… - Cells, 2023 - mdpi.com
Testis stimulation with follicle-stimulating hormone (FSH) is one of the empirical treatments
proposed for male idiopathic infertility, although reliable markers to predict its efficacy are …

Current global status of male reproductive health

CJ De Jonge, CLR Barratt, RJ Aitken… - Human …, 2024 - academic.oup.com
BACKGROUND The widespread interest in male reproductive health (MRH), fueled by
emerging evidence, such as the global decline in sperm counts, has intensified concerns …