[PDF][PDF] A cellular taxonomy of the adult human spinal cord
The mammalian spinal cord functions as a community of cell types for sensory processing,
autonomic control, and movement. While animal models have advanced our understanding …
autonomic control, and movement. While animal models have advanced our understanding …
Axonal growth inhibitors and their receptors in spinal cord injury: from biology to clinical translation
SS Chambel, CD Cruz - Neural Regeneration Research, 2023 - journals.lww.com
Axonal growth inhibitors are released during traumatic injuries to the adult mammalian
central nervous system, including after spinal cord injury. These molecules accumulate at …
central nervous system, including after spinal cord injury. These molecules accumulate at …
Single-cell analysis reveals region-heterogeneous responses in rhesus monkey spinal cord with complete injury
Y Fan, X Wu, S Han, Q Zhang, Z Sun, B Chen… - Nature …, 2023 - nature.com
Spinal cord injury (SCI) leads to severe sensory and motor dysfunction below the lesion.
However, the cellular dynamic responses and heterogeneity across different regions below …
However, the cellular dynamic responses and heterogeneity across different regions below …
Age-dependent immune and lymphatic responses after spinal cord injury
Spinal cord injury (SCI) causes lifelong debilitating conditions. Previous works demonstrated
the essential role of the immune system in recovery after SCI. Here, we explored the …
the essential role of the immune system in recovery after SCI. Here, we explored the …
[PDF][PDF] Deep scRNA sequencing reveals a broadly applicable Regeneration Classifier and implicates antioxidant response in corticospinal axon regeneration
HJ Kim, JM Saikia, KMA Monte, E Ha… - Neuron, 2023 - cell.com
Despite substantial progress in understanding the biology of axon regeneration in the CNS,
our ability to promote regeneration of the clinically important corticospinal tract (CST) after …
our ability to promote regeneration of the clinically important corticospinal tract (CST) after …
[HTML][HTML] Targeting Mitochondrial Oxidative Stress: Potential Neuroprotective Therapy for Spinal Cord Injury
Z He, C Zhang, JX Liang, FF Zheng, XY Qi… - Journal of Integrative …, 2023 - imrpress.com
Spinal cord injury (SCI) is a serious central nervous system (CNS) injury disease related to
hypoxia-ischemia and inflammation. It is characterized by excessive reactive oxygen …
hypoxia-ischemia and inflammation. It is characterized by excessive reactive oxygen …
Single-nucleus transcriptomic mapping uncovers targets for traumatic brain injury
Q Yang, L Zhang, M Li, Y Xu, X Chen, R Yuan… - Genome …, 2023 - genome.cshlp.org
The subventricular zone (SVZ) is a neurogenic niche that contributes to homeostasis and
repair after brain injury. However, the effects of mild traumatic brain injury (mTBI) on the …
repair after brain injury. However, the effects of mild traumatic brain injury (mTBI) on the …
Diurnal proteome profile of the mouse cerebral cortex: Conditional deletion of the Bmal1 circadian clock gene elevates astrocyte protein levels and cell abundance in …
T Bering, C Gadgaard, H Vorum, B Honoré, MF Rath - Glia, 2023 - Wiley Online Library
Circadian oscillators, defined by cellular 24 h clock gene rhythms, are found throughout the
brain. Cerebral cortex‐specific conditional knockout of the clock gene Bmal1 (Bmal1 CKO) …
brain. Cerebral cortex‐specific conditional knockout of the clock gene Bmal1 (Bmal1 CKO) …
Zinc regulates a specific subpopulation of VEGFA+ microglia to improve the hypoxic microenvironment for functional recovery after spinal cord injury
H Deng, Y Liu, Z Shi, J Yang, C Liu, X Mei - International …, 2023 - Elsevier
Introduction Spinal cord injury (SCI) is a central nervous system injury that is primarily
traumatic and manifests as autonomic dysfunction below the level of injury. Our previous …
traumatic and manifests as autonomic dysfunction below the level of injury. Our previous …
Microglial cannabinoid receptor type 1 mediates social memory deficits in mice produced by adolescent THC exposure and 16p11. 2 duplication
Adolescent cannabis use increases the risk for cognitive impairments and psychiatric
disorders. Cannabinoid receptor type 1 (Cnr1) is expressed not only in neurons and …
disorders. Cannabinoid receptor type 1 (Cnr1) is expressed not only in neurons and …