Advances and utility of the human plasma proteome
The study of proteins circulating in blood offers tremendous opportunities to diagnose,
stratify, or possibly prevent diseases. With recent technological advances and the urgent …
stratify, or possibly prevent diseases. With recent technological advances and the urgent …
Multilevel omics for the discovery of biomarkers and therapeutic targets for stroke
Despite many years of research, no biomarkers for stroke are available to use in clinical
practice. Progress in high-throughput technologies has provided new opportunities to …
practice. Progress in high-throughput technologies has provided new opportunities to …
Mass spectrometry-based plasma proteomics: considerations from sample collection to achieving translational data
The proteomic analysis of human blood and blood-derived products (eg, plasma) offers an
attractive avenue to translate research progress from the laboratory into the clinic. However …
attractive avenue to translate research progress from the laboratory into the clinic. However …
Stroke proteomics: from discovery to diagnostic and therapeutic applications
K Hochrainer, W Yang - Circulation research, 2022 - Am Heart Assoc
Stroke remains a leading cause of death and disability, with limited therapeutic options and
suboptimal tools for diagnosis and prognosis. High throughput technologies such as …
suboptimal tools for diagnosis and prognosis. High throughput technologies such as …
Sex differences in presentation and outcome after an acute transient or minor neurologic event
Importance Sex differences have been described in the presentation, care, and outcomes
among people with acute ischemic strokes, but these differences are less understood for …
among people with acute ischemic strokes, but these differences are less understood for …
Proteomics in thrombosis and hemostasis
N Letunica, S Van Den Helm… - Thrombosis and …, 2022 - thieme-connect.com
Proteomics, the simultaneous study of all proteins in a given cell, tissue or organism, is an
innovative approach used to identify novel markers for diagnosis, prognosis and the …
innovative approach used to identify novel markers for diagnosis, prognosis and the …
[HTML][HTML] Multiplex quantitation of 270 plasma protein markers to identify a signature for early detection of colorectal cancer
M Bhardwaj, K Weigl, K Tikk, T Holland-Letz… - European Journal of …, 2020 - Elsevier
Blood-based protein biomarker signatures might be an alternative or supplement to existing
methods for early detection of colorectal cancer (CRC) for population-based screening. The …
methods for early detection of colorectal cancer (CRC) for population-based screening. The …
Association between duration of transient neurological events and diffusion‐weighted brain lesions
Background The relationship between duration of transient neurological events and
presence of diffusion‐weighted lesions by symptom type is unclear. Methods and Results …
presence of diffusion‐weighted lesions by symptom type is unclear. Methods and Results …
Biobanking for genomic and personalized health research: participant perceptions and preferences
R Barnes, K Votova, V Rahimzadeh… - Biopreservation and …, 2020 - liebertpub.com
Introduction: Biospecimens and associated data are invaluable tools in Genomics and
Personalized Health (GAPH) research and can aid in the discovery of disease etiology and …
Personalized Health (GAPH) research and can aid in the discovery of disease etiology and …
Presenting Symptoms and Diffusion-Weighted MRI Positivity by Time After Transient Neurologic Events: A Pooled Analysis of 3 Cohort Studies
Background and Objective The association between focal vs nonfocal presenting symptom
and diffusion-weighted imaging (DWI) positivity in relation to onset-to-imaging time in …
and diffusion-weighted imaging (DWI) positivity in relation to onset-to-imaging time in …