The biophysics and cell biology of lipid droplets
Lipid droplets are intracellular organelles that are found in most cells, where they have
fundamental roles in metabolism. They function prominently in storing oil-based reserves of …
fundamental roles in metabolism. They function prominently in storing oil-based reserves of …
The health benefits of dietary fiber: beyond the usual suspects of type 2 diabetes mellitus, cardiovascular disease and colon cancer
MM Kaczmarczyk, MJ Miller, GG Freund - Metabolism, 2012 - Elsevier
Dietary fiber (DF) is deemed to be a key component in healthy eating. DF is not a static
collection of undigestible plant materials that pass untouched or unencumbered through the …
collection of undigestible plant materials that pass untouched or unencumbered through the …
Recent advances in hepatocellular carcinoma therapy
Hepatocellular carcinoma (HCC), also called malignant hepatoma, is one of the deadliest
cancers due to its complexities, reoccurrence after surgical resection, metastasis and …
cancers due to its complexities, reoccurrence after surgical resection, metastasis and …
Yarrowia lipolytica as a model for bio-oil production
A Beopoulos, J Cescut, R Haddouche… - Progress in lipid …, 2009 - Elsevier
The yeast Yarrowialipolytica has developed very efficient mechanisms for breaking down
and using hydrophobic substrates. It is considered an oleaginous yeast, based on its ability …
and using hydrophobic substrates. It is considered an oleaginous yeast, based on its ability …
Not just fat: the structure and function of the lipid droplet
T Fujimoto, RG Parton - Cold Spring Harbor perspectives …, 2011 - cshperspectives.cshlp.org
Lipid droplets (LDs) are independent organelles that are composed of a lipid ester core and
a surface phospholipid monolayer. Recent studies have revealed many new proteins …
a surface phospholipid monolayer. Recent studies have revealed many new proteins …
[HTML][HTML] Autophagy, lipophagy and lysosomal lipid storage disorders
Autophagy is a catabolic process with an essential function in the maintenance of cellular
and tissue homeostasis. It is primarily recognised for its role in the degradation of …
and tissue homeostasis. It is primarily recognised for its role in the degradation of …
An Overview of Hormone‐Sensitive Lipase (HSL)
AR Althaher - The Scientific World Journal, 2022 - Wiley Online Library
Hormone‐sensitive lipase (HSL) is a pivotal enzyme that mediates triglyceride hydrolysis to
provide free fatty acids and glycerol in adipocytes in a hormonally controlled lipolysis …
provide free fatty acids and glycerol in adipocytes in a hormonally controlled lipolysis …
[HTML][HTML] Coupling of lipolysis and de novo lipogenesis in brown, beige, and white adipose tissues during chronic β3-adrenergic receptor activation
Chronic activation of β3-adrenergic receptors (β3-ARs) expands the catabolic activity of both
brown and white adipose tissue by engaging uncoupling protein 1 (UCP1)-dependent and …
brown and white adipose tissue by engaging uncoupling protein 1 (UCP1)-dependent and …
[HTML][HTML] A twist of FATe: Lipid droplets and inflammatory lipid mediators
E Jarc, T Petan - Biochimie, 2020 - Elsevier
Lipid droplets are fat storage organelles present in most eukaryotic cells. They consist of a
neutral lipid core containing mostly triglycerides and sterol esters and covered by a …
neutral lipid core containing mostly triglycerides and sterol esters and covered by a …
[HTML][HTML] The G0/G1 switch gene 2 regulates adipose lipolysis through association with adipose triglyceride lipase
X Yang, X Lu, M Lombès, GB Rha, YI Chi, TM Guerin… - Cell metabolism, 2010 - cell.com
Adipose triglyceride lipase (ATGL) is the rate-limiting enzyme for triacylglycerol (TAG)
hydrolysis in adipocytes. The precise mechanisms whereby ATGL is regulated remain …
hydrolysis in adipocytes. The precise mechanisms whereby ATGL is regulated remain …