The Legionella pneumophila replication vacuole: making a cosy niche inside host cells

RR Isberg, TJ O'connor, M Heidtman - Nature Reviews Microbiology, 2009 - nature.com
The pathogenesis of Legionella pneumophila is derived from its growth within lung
macrophages after aerosols are inhaled from contaminated water sources. Interest in this …

Expression of highly toxic genes in E. coli: special strategies and genetic tools

F Saïda, M Uzan, B Odaert… - Current Protein and …, 2006 - ingentaconnect.com
Escherichia coli (E. coli) remains the most efficient widely-used host for recombinant protein
production. Well-known genetics, high transformation efficiency, cultivation simplicity …

A Yersinia effector and a Pseudomonas avirulence protein define a family of cysteine proteases functioning in bacterial pathogenesis

F Shao, PM Merritt, Z Bao, RW Innes, JE Dixon - Cell, 2002 - cell.com
A Yersinia effector known as YopT and a Pseudomonas avirulence protein known as
AvrPphB define a family of 19 proteins involved in bacterial pathogenesis. We show that …

[HTML][HTML] The mechanism of action of the Pseudomonas aeruginosa‐encoded type III cytotoxin, ExoU

H Sato, DW Frank, CJ Hillard, JB Feix… - The EMBO …, 2003 - embopress.org
Pseudomonas aeruginosa delivers the toxin ExoU to eukaryotic cells via a type III secretion
system. Intoxication with ExoU is associated with lung injury, bacterial dissemination and …

[HTML][HTML] Pseudomonas type III effector AvrPtoB induces plant disease susceptibility by inhibition of host programmed cell death

RB Abramovitch, YJ Kim, S Chen, MB Dickman… - The EMBO …, 2003 - embopress.org
The AvrPtoB type III effector protein is conserved among diverse genera of plant pathogens
suggesting it plays an important role in pathogenesis. Here we report that Pseudomonas …

[HTML][HTML] Identification of a bacterial type III effector family with G protein mimicry functions

NM Alto, F Shao, CS Lazar, RL Brost, G Chua, S Mattoo… - Cell, 2006 - cell.com
Many bacterial pathogens use the type III secretion system to inject" effector" proteins into
host cells. Here, we report the identification of a 24 member effector protein family found in …

Legionella Eukaryotic-Like Type IV Substrates Interfere with Organelle Trafficking

KS de Felipe, RT Glover, X Charpentier… - PLoS …, 2008 - journals.plos.org
Legionella pneumophila, the causative agent of Legionnaires' disease, evades phago-
lysosome fusion in mammalian and protozoan hosts to create a suitable niche for …

Pathogen effector protein screening in yeast identifies Legionella factors that interfere with membrane trafficking

N Shohdy, JA Efe, SD Emr… - Proceedings of the …, 2005 - National Acad Sciences
Legionella pneumophila invades and replicates intracellularly in human and protozoan
hosts. The bacteria use the Icm/Dot type IVB secretion system to translocate effectors that …

Bacterial mycophagy: definition and diagnosis of a unique bacterial–fungal interaction

JHJ Leveau, GM Preston - New Phytologist, 2008 - Wiley Online Library
This review analyses the phenomenon of bacterial mycophagy, which we define as a set of
phenotypic behaviours that enable bacteria to obtain nutrients from living fungi and thus …

Large‐scale identification of Legionella pneumophila Dot/Icm substrates that modulate host cell vesicle trafficking pathways

M Heidtman, EJ Chen, MY Moy… - Cellular …, 2009 - Wiley Online Library
The bacterial pathogen Legionella pneumophila replicates in a specialized vacuole within
host cells. Establishment of the replication vacuole depends on the Dot/Icm translocation …