Recent developments in azole compounds as antibacterial and antifungal agents

XM Peng, GX Cai, CH Zhou - Current Topics in Medicinal …, 2013 - ingentaconnect.com
Azole compounds are an important class of nitrogen heterocycles with electron-rich
property. This special structure endows azole-based derivatives easily bind with the …

[HTML][HTML] Synthesis and inhibition profiles of N-benzyl-and N-allyl aniline derivatives against carbonic anhydrase and acetylcholinesterase–A molecular docking study

I Mahmudov, Y Demir, Y Sert, Y Abdullayev… - Arabian Journal of …, 2022 - Elsevier
The alkyl and aryl derivatives of aniline are important starting materials in fine organic
synthesis. Allyl bromide and benzyl chloride were taken as substrates for the alkylation …

Investigation of inhibitory properties of some hydrazone compounds on hCA I, hCA II and AChE enzymes

K Kucukoglu, HI Gul, P Taslimi, I Gulcin… - Bioorganic chemistry, 2019 - Elsevier
Recently, inhibition of carbonic anhydrase (hCA) and acetylcholinesterase (AChE) have
appeared as a promising approach for pharmacological intervention in a variety of disorders …

Antimicrobial activity and a SAR study of some novel benzimidazole derivatives bearing hydrazone moiety

Y Özkay, Y Tunalı, H Karaca, İ Işıkdağ - European journal of medicinal …, 2010 - Elsevier
In this study 12 novel benzimidazole compounds bearing hydrazone moiety were
synthesized in order to investigate their possible antibacterial and antifungal activity …

Efficient synthesis, antibacterial, antifungal, antioxidant and cytotoxicity study of 2‐(2‐hydrazineyl) thiazole derivatives

VA Adole, RA More, BS Jagdale, TB Pawar… - …, 2020 - Wiley Online Library
In the present investigation, an alluring green PEG‐400 mediated one‐pot synthesis of
novel 2‐(2‐hydrazinyl) thiazole derivatives from 1, 2, 6, 7‐tetrahydro‐8H‐indeno [5, 4‐b] …

[PDF][PDF] Therapeutic review exploring antimicrobial potential of hydrazones as promising lead

G Uppal, S Bala, S Kamboj, M Saini - Der Pharma Chemica, 2011 - researchgate.net
This review includes detailed study of structures of various hydrazones synthesized and
evaluated for their antimicrobial activity. Hydrazone is a class of organic compounds with …

Design, synthesis and mode of action of some benzothiazole derivatives bearing an amide moiety as antibacterial agents

M Singh, SK Singh, M Gangwar, G Nath, SK Singh - RSC advances, 2014 - pubs.rsc.org
In this study ten benzothiazole derivatives bearing the amide moiety were designed,
synthesized and evaluated for their antibacterial activity and possible mode of action …

Design, Synthesis, and Pharmacological Evaluation of N-Acylhydrazones and Novel Conformationally Constrained Compounds as Selective and Potent Orally Active …

AE Kümmerle, M Schmitt, SVS Cardozo… - Journal of medicinal …, 2012 - ACS Publications
Among a small series of tested N-acylhydrazones (NAHs), the compound 8a was selected
as a selective submicromolar phosphodiesterase-4 (PDE4) inhibitor associated with anti …

Synthesis of some new [1, 2, 4] triazolo [3, 4-b][1, 3, 4] thiadiazines and [1, 2, 4] triazolo [3, 4-b][1, 3, 4] thiadiazoles starting from 5-nitro-2-furoic acid and evaluation of …

SMI Badr, RM Barwa - Bioorganic & medicinal chemistry, 2011 - Elsevier
New series of fused 1, 2, 4-triazoles such as, 6-(aryl)-3-(5-nitrofuran-2-yl)-5, 6-dihydro-[1, 2,
4] triazolo [3, 4-b][1, 3, 4] thiadiazoles 4–8, 6-(alkyl/aryl amino)-3-(5-nitrofuran-2-yl)-[1, 2, 4] …

Synthesis, structural and spectroscopic features, and investigation of bioactive nature of a novel organic-inorganic hybrid material 1H-1, 2, 4-triazole-4-ium …

S Gatfaoui, N Issaoui, A Mezni, F Bardak… - Journal of Molecular …, 2017 - Elsevier
The novel inorganic-organic hybrid material 1H-1, 2, 4-triazole-4-ium trioxonitrate (TAN)
have been elaborated and crystallized to the monoclinic system with space group P2 1/c …