Abstract Background New Approach Methodologies (NAMs) comprise in silico and in vitro
methods applied as alternative to animal testing. Even though NAMs are already fully …

In silico methods and models are increasingly used for predicting properties of chemicals for
hazard identification and hazard characterisation in the absence of experimental toxicity …

In 2015, EFSA established a temporary tolerable daily intake (t‐TDI) for BPA of 4 μg/kg body
weight (bw) per day. In 2016, the European Commission mandated EFSA to re‐evaluate the …

This Guidance document describes harmonised risk assessment methodologies for
combined exposure to multiple chemicals for all relevant areas within EFSA's remit, ie …

This Guidance describes how to perform hazard identification for endocrine‐disrupting
properties by following the scientific criteria which are outlined in Commission Delegated …

Uncertainty analysis is the process of identifying limitations in scientific knowledge and
evaluating their implications for scientific conclusions. It is therefore relevant in all EFSA's …

Following a request from the European Commission, the EFSA Panel on Nutrition, Novel
Foods and Food Allergens (NDA) derived dietary reference values (DRV s) for sodium …

Read-across is one of the most frequently used alternative tools for hazard assessment, in
particular for complex endpoints such as repeated dose or developmental and reproductive …

This guidance document provides harmonised and flexible methodologies to apply scientific
criteria and prioritisation methods for grouping chemicals into assessment groups for human …

While whole animal studies have their place in risk assessment of food and feed
components, it is thought that more modern approaches such as human focused new …