[HTML][HTML] Implementing New Approach Methodologies (NAMs) in food safety assessments: Strategic objectives and actions taken by the European Food Safety …
I Cattaneo, MC Astuto, M Binaglia, Y Devos… - Trends in Food Science …, 2023 - Elsevier
Abstract Background New Approach Methodologies (NAMs) comprise in silico and in vitro
methods applied as alternative to animal testing. Even though NAMs are already fully …
methods applied as alternative to animal testing. Even though NAMs are already fully …
[HTML][HTML] Integrating in silico models and read-across methods for predicting toxicity of chemicals: A step-wise strategy
In silico methods and models are increasingly used for predicting properties of chemicals for
hazard identification and hazard characterisation in the absence of experimental toxicity …
hazard identification and hazard characterisation in the absence of experimental toxicity …
Re‐evaluation of the risks to public health related to the presence of bisphenol A (BPA) in foodstuffs
EFSA Panel on Food Contact Materials … - EFSA …, 2023 - Wiley Online Library
In 2015, EFSA established a temporary tolerable daily intake (t‐TDI) for BPA of 4 μg/kg body
weight (bw) per day. In 2016, the European Commission mandated EFSA to re‐evaluate the …
weight (bw) per day. In 2016, the European Commission mandated EFSA to re‐evaluate the …
Guidance on harmonised methodologies for human health, animal health and ecological risk assessment of combined exposure to multiple chemicals
EFSA Scientific Committee, SJ More, V Bampidis… - Efsa …, 2019 - Wiley Online Library
This Guidance document describes harmonised risk assessment methodologies for
combined exposure to multiple chemicals for all relevant areas within EFSA's remit, ie …
combined exposure to multiple chemicals for all relevant areas within EFSA's remit, ie …
Guidance for the identification of endocrine disruptors in the context of Regulations (EU) No 528/2012 and (EC) No 1107/2009
… Chemical Agency (ECHA) and European Food … - EFSA …, 2018 - Wiley Online Library
This Guidance describes how to perform hazard identification for endocrine‐disrupting
properties by following the scientific criteria which are outlined in Commission Delegated …
properties by following the scientific criteria which are outlined in Commission Delegated …
Guidance on uncertainty analysis in scientific assessments
EFSA Scientific Committee, D Benford… - Efsa …, 2018 - Wiley Online Library
Uncertainty analysis is the process of identifying limitations in scientific knowledge and
evaluating their implications for scientific conclusions. It is therefore relevant in all EFSA's …
evaluating their implications for scientific conclusions. It is therefore relevant in all EFSA's …
Dietary reference values for sodium
EFSA Panel on Nutrition, Novel Foods and Food … - EFSA …, 2019 - Wiley Online Library
Following a request from the European Commission, the EFSA Panel on Nutrition, Novel
Foods and Food Allergens (NDA) derived dietary reference values (DRV s) for sodium …
Foods and Food Allergens (NDA) derived dietary reference values (DRV s) for sodium …
Towards grouping concepts based on new approach methodologies in chemical hazard assessment: the read-across approach of the EU-ToxRisk project
SE Escher, H Kamp, SH Bennekou, A Bitsch… - Archives of …, 2019 - Springer
Read-across is one of the most frequently used alternative tools for hazard assessment, in
particular for complex endpoints such as repeated dose or developmental and reproductive …
particular for complex endpoints such as repeated dose or developmental and reproductive …
Guidance Document on Scientific criteria for grouping chemicals into assessment groups for human risk assessment of combined exposure to multiple chemicals
EFSA Scientific Committee, SJ More, V Bampidis… - EFSA …, 2021 - Wiley Online Library
This guidance document provides harmonised and flexible methodologies to apply scientific
criteria and prioritisation methods for grouping chemicals into assessment groups for human …
criteria and prioritisation methods for grouping chemicals into assessment groups for human …
Development of a roadmap for action on new approach methodologies in risk assessment
SE Escher, F Partosch, S Konzok… - EFSA Supporting …, 2022 - Wiley Online Library
While whole animal studies have their place in risk assessment of food and feed
components, it is thought that more modern approaches such as human focused new …
components, it is thought that more modern approaches such as human focused new …