Calcineurin inhibitors cyclosporin A and tacrolimus protect against podocyte injury induced by puromycin aminonucleoside in rodent models

X Shen, H Jiang, M Ying, Z Xie, X Li, H Wang, J Zhao… - Scientific reports, 2016 - nature.com
Podocyte injury and the appearance of proteinuria are features of minimal-change disease
(MCD). Cyclosporin A (CsA) and tacrolimus (FK506) has been reported to reduce …

Cyclosporine and steroid therapy in children with steroid-resistant nephrotic syndrome

Y Hamasaki, N Yoshikawa, S Hattori, S Sasaki… - Pediatric …, 2009 - Springer
We conducted a prospective, multicenter trial to evaluate the efficacy and safety of a 12-
month course of cyclosporine in children with steroid-resistant nephrotic syndrome (SRNS) …

Corticosteroid-resistant nephrotic syndrome with focal and segmental glomerulosclerosis: an update of treatment options for children

JHH Ehrich, L Pape, M Schiffer - Pediatric Drugs, 2008 - Springer
Corticosteroid-resistant nephrotic syndrome (CRNS) with focal and segmental
glomerulosclerosis (FSGS) is a heterogeneous disorder and the most severe and frequent …

Alterations in the expression of signal-transducing CD3ζ chain in T cells from patients with chronic inflammatory/autoimmune diseases

L Ciszak, E Pawlak, A Kosmaczewska… - Archivum immunologiae …, 2007 - Springer
The CD3ζ chain, a component of the T cell receptor (TCR)/CD3 complex, is considered to be
a limiting factor in the assembly and transport of the TCR/CD3 complex to the cell surface …

Steroid-resistant nephrotic syndrome: long-term evolution after sequential therapy

A Peña, J Bravo, M Melgosa, C Fernandez… - Pediatric …, 2007 - Springer
We present a retrospective study of 30 children of mean age 3.02±1.81 years with steroid-
resistant nephrotic syndrome (SRNS) treated with intravenous injection of …

Refractory focal segmental glomerulosclerosis in the adult: complete and sustained remissions of two episodes of nephrotic syndrome after a single dose of rituximab

M Marasà, P Cravedi, B Ruggiero… - Case Reports, 2014 - casereports.bmj.com
Rituximab therapy may achieve remission of proteinuria in children or adolescents with
refractory focal segmental glomerulosclerosis (FSGS), but its effectiveness in adults is …

Хронический гломерулонефрит: аргументы в пользу применения циклоспорина

ЛВ Козловская - Клиническая нефрология, 2010 - elibrary.ru
Обсуждаются показания к применению циклоспорина для лечения хронического
гломерулонефрита. Представлено обоснование его эффективности при нефропатии …

Membranous nephropathy in a 13-year-old boy with common variable immunodeficiency

HE Yim, KH Yoo - Journal of Korean medical science, 2012 - synapse.koreamed.org
Various forms of hypogammaglobulinemia can occur in patients with autoimmune diseases
and vice versa. We report a 13-yr-old boy with membranous nephropathy and common …

Clinicopathological correlation and treatment response of primary focal segmental glomerulosclerosis in adults and adolescents

J Dhanapriya, T Dineshkumar… - Indian Journal of …, 2016 - journals.lww.com
The incidence of focal segmental glomerulosclerosis (FSGS) is approximately 10% in
children< 6 years, 20% in adolescents, and 20-25% in adults. A retrospective observational …

Tacrolimus-induced HUS: an unusual cause of acute renal failure in nephrotic syndrome

VB Pandirikkal, M Jain, S Gulati - Pediatric nephrology, 2007 - Springer
Acute renal failure (ARF) is an uncommon complication in children with nephrotic syndrome.
We report here the case of a 10-year-old male child with primary steroid-resistant nephrotic …