Partial least squares-discriminant analysis (PLS-DA) for classification of high-dimensional (HD) data: a review of contemporary practice strategies and knowledge …

LC Lee, CY Liong, AA Jemain - Analyst, 2018 - pubs.rsc.org
Partial least squares-discriminant analysis (PLS-DA) is a versatile algorithm that can be
used for predictive and descriptive modelling as well as for discriminative variable selection …

A tutorial review: Metabolomics and partial least squares-discriminant analysis–a marriage of convenience or a shotgun wedding

PS Gromski, H Muhamadali, DI Ellis, Y Xu, E Correa… - Analytica chimica …, 2015 - Elsevier
The predominance of partial least squares-discriminant analysis (PLS-DA) used to analyze
metabolomics datasets (indeed, it is the most well-known tool to perform classification and …

[HTML][HTML] Metformin enhances autophagy and normalizes mitochondrial function to alleviate aging-associated inflammation

LP Bharath, M Agrawal, G McCambridge, DA Nicholas… - Cell metabolism, 2020 - cell.com
Age is a non-modifiable risk factor for the inflammation that underlies age-associated
diseases; thus, anti-inflammaging drugs hold promise for increasing health span. Cytokine …

Multiple skin lesions diagnostics via integrated deep convolutional networks for segmentation and classification

MA Al-Masni, DH Kim, TS Kim - Computer methods and programs in …, 2020 - Elsevier
Background and objective Computer automated diagnosis of various skin lesions through
medical dermoscopy images remains a challenging task. Methods In this work, we propose …

[HTML][HTML] Human metabolome variation along the upper intestinal tract

J Folz, RN Culver, JM Morales, J Grembi… - Nature …, 2023 - nature.com
Most processing of the human diet occurs in the small intestine. Metabolites in the small
intestine originate from host secretions, plus the ingested exposome and microbial …

Skin lesion segmentation in dermoscopy images via deep full resolution convolutional networks

MA Al-Masni, MA Al-Antari, MT Choi, SM Han… - Computer methods and …, 2018 - Elsevier
Background and objective Automatic segmentation of skin lesions in dermoscopy images is
still a challenging task due to the large shape variations and indistinct boundaries of the …

A fully integrated computer-aided diagnosis system for digital X-ray mammograms via deep learning detection, segmentation, and classification

MA Al-Antari, MA Al-Masni, MT Choi, SM Han… - International journal of …, 2018 - Elsevier
A computer-aided diagnosis (CAD) system requires detection, segmentation, and
classification in one framework to assist radiologists efficiently in an accurate diagnosis. In …

Simultaneous detection and classification of breast masses in digital mammograms via a deep learning YOLO-based CAD system

MA Al-Masni, MA Al-Antari, JM Park, G Gi… - Computer methods and …, 2018 - Elsevier
Background and objective Automatic detection and classification of the masses in
mammograms are still a big challenge and play a crucial role to assist radiologists for …

Analysis of the human adult urinary metabolome variations with age, body mass index, and gender by implementing a comprehensive workflow for univariate and …

EA Thévenot, A Roux, Y Xu, E Ezan… - Journal of proteome …, 2015 - ACS Publications
Urine metabolomics is widely used for biomarker research in the fields of medicine and
toxicology. As a consequence, characterization of the variations of the urine metabolome …

[HTML][HTML] metaX: a flexible and comprehensive software for processing metabolomics data

B Wen, Z Mei, C Zeng, S Liu - BMC bioinformatics, 2017 - Springer
Background Non-targeted metabolomics based on mass spectrometry enables high-
throughput profiling of the metabolites in a biological sample. The large amount of data …