Neuronal calcium sensor proteins: generating diversity in neuronal Ca2+ signalling

RD Burgoyne - Nature Reviews Neuroscience, 2007 - nature.com
In neurons, intracellular calcium signals have crucial roles in activating neurotransmitter
release and in triggering alterations in neuronal function. Calmodulin has been widely …

Calcium sensors in neuronal function and dysfunction

RD Burgoyne, N Helassa… - Cold Spring Harbor …, 2019 - cshperspectives.cshlp.org
Calcium signaling in neurons as in other cell types can lead to varied changes in cellular
function. Neuronal Ca2+ signaling processes have also become adapted to modulate the …

Uncovering molecular biomarkers that correlate cognitive decline with the changes of hippocampus' gene expression profiles in Alzheimer's disease

M Gomez Ravetti, OA Rosso, R Berretta, P Moscato - PloS one, 2010 - journals.plos.org
Background Alzheimer's disease (AD) is characterized by a neurodegenerative progression
that alters cognition. On a phenotypical level, cognition is evaluated by means of the …

Visinin-like proteins (VSNLs): interaction partners and emerging functions in signal transduction of a subfamily of neuronal Ca2+-sensor proteins

KH Braunewell, AJK Szanto - Cell and tissue research, 2009 - Springer
The visinin-like protein (VSNL) subfamily, including VILIP-1 (the founder protein), VILIP-2,
VILIP-3, hippocalcin, and neurocalcin δ, constitute a highly homologous subfamily of …

The molecular basis for the calcium-dependent slow afterhyperpolarization in CA1 hippocampal pyramidal neurons

G Sahu, RW Turner - Frontiers in Physiology, 2021 - frontiersin.org
Neuronal signal transmission depends on the frequency, pattern, and timing of spike output,
each of which are shaped by spike afterhyperpolarizations (AHPs). There are classically …

Arf1 directly recruits the Pik1-Frq1 PI4K complex to regulate the final stages of Golgi maturation

CM Highland, JC Fromme - Molecular Biology of the Cell, 2021 - Am Soc Cell Biol
Proper Golgi complex function depends on the activity of Arf1, a GTPase whose effectors
assemble and transport outgoing vesicles. Phosphatidylinositol 4-phosphate (PI4P) …

[HTML][HTML] NCS-1 is a regulator of calcium signaling in health and disease

GR Boeckel, BE Ehrlich - Biochimica et Biophysica Acta (BBA)-Molecular …, 2018 - Elsevier
Abstract Neuronal Calcium Sensor-1 (NCS-1) is a highly conserved calcium binding protein
which contributes to the maintenance of intracellular calcium homeostasis and regulation of …

The diversity of calcium sensor proteins in the regulation of neuronal function

HV McCue, LP Haynes… - Cold Spring Harbor …, 2010 - cshperspectives.cshlp.org
Calcium signaling in neurons as in other cell types mediates changes in gene expression,
cell growth, development, survival, and cell death. However, neuronal Ca2+ signaling …

Understanding the physiological roles of the neuronal calcium sensor proteins

RD Burgoyne, LP Haynes - Molecular brain, 2012 - Springer
Calcium signalling plays a crucial role in the control of neuronal function and plasticity.
Changes in neuronal Ca 2+ concentration are detected by Ca 2+-binding proteins that can …

[HTML][HTML] Sense and specificity in neuronal calcium signalling

RD Burgoyne, LP Haynes - Biochimica et Biophysica Acta (BBA)-Molecular …, 2015 - Elsevier
Abstract Changes in the intracellular free calcium concentration ([Ca 2+] i) in neurons
regulate many and varied aspects of neuronal function over time scales from microseconds …