Antibiotics are the commonest cause of life-threatening immune-mediated drug reactions
that are considered off-target, including anaphylaxis, and organ-specific and severe …

Importance β-Lactam antibiotics are among the safest and most effective antibiotics. Many
patients report allergies to these drugs that limit their use, resulting in the use of broad …

Antimicrobial agents are some of the most widely, and often injudiciously, used therapeutic
drugs worldwide. Important considerations when prescribing antimicrobial therapy include …

These guidelines for the treatment of persons who have or are at risk for sexually transmitted
diseases (STDs) were updated by CDC after consultation with a group of professionals …

The penicillin allergy label has been consistently linked with deleterious effects that span the
health care spectrum, including suboptimal clinical outcomes, the emergence of bacterial …

Background Self-reported penicillin allergy infrequently reflects an inability to tolerate
penicillins. Inpatients reporting penicillin allergy receive alternative antibiotics that might be …

Background Reported penicillin allergy rarely reflects penicillin intolerance. Failure to
address inpatient penicillin allergies results in more broad-spectrum antibiotic use, treatment …

Background Prescribing antibiotics to patients with a history of penicillin allergy is common
in clinical practice. Opting for non-beta-lactam antibiotics has its inconveniences and is often …

BACKGROUND: Penicillin allergy is commonly reported in the pediatric emergency
department (ED). True penicillin allergy is rare, yet the diagnosis results from the denial of …

Abstract Background Antibiotic allergy labels (AALs), reported by up to 25% of hospitalized
patients, are a significant barrier to appropriate prescribing and a focus of antimicrobial …