Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system that
involves demyelination and axonal degeneration. Although substantial progress has been …

The immune system plays a significant role in multiple sclerosis. While MS was historically
thought to be T cell-mediated, multiple pieces of evidence now support the view that B cells …

Objective To assess over 3 years of follow-up the effects of maintaining or switching to
ocrelizumab (OCR) therapy on clinical and MRI outcomes and safety measures in the open …

Until recently, in the pathogenesis of Multiple Sclerosis (MS), the contribution of B cells has
been largely underestimated, and the disease was considered a T-cell-mediated disorder …

Despite the availability of a lot of effective disease-modifying drugs, multiple sclerosis
(MS)(in particular the progressive forms) still represents an important unmet medical need …

Increased inflammation in the cerebral meninges is associated with extensive subpial
cortical grey matter pathology in the forebrain and a more severe disease course in a …

Objective To determine whether autologous hematopoietic stem cell transplantation
(aHSCT) is able to induce durable disease remission in people with multiple sclerosis (MS) …

Multiple sclerosis is a chronic autoimmune disease of the central nervous system that results
in varying degrees of disability. Progressive multiple sclerosis, characterized by a steady …

Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the
central nervous system (CNS) affecting more than two million people worldwide. In MS …

Background: Rituximab, an anti-CD20 monoclonal antibody leading to B lymphocyte
depletion, is increasingly used as an off-label treatment option for multiple sclerosis (MS) …