Current concepts and future directions for the assessment of autoantibodies to cellular antigens referred to as anti‐nuclear antibodies

M Mahler, PL Meroni, X Bossuyt… - Journal of immunology …, 2014 - Wiley Online Library
The detection of autoantibodies that target intracellular antigens, commonly termed anti‐
nuclear antibodies (ANA), is a serological hallmark in the diagnosis of systemic autoimmune …

Current and emerging techniques for ANCA detection in vasculitis

E Csernok, F Moosig - Nature Reviews Rheumatology, 2014 - nature.com
Detection of antineutrophil cytoplasmic antibodies (ANCAs) is a well-established diagnostic
test used to evaluate suspected necrotizing vasculitis of small blood vessels. Conditions …

Genotypic and phenotypic characteristics associated with biofilm formation by human clinical Escherichia coli isolates of different pathotypes

J Schiebel, A Böhm, J Nitschke… - Applied and …, 2017 - Am Soc Microbiol
Bacterial biofilm formation is a widespread phenomenon and a complex process requiring a
set of genes facilitating the initial adhesion, maturation, and production of the extracellular …

[HTML][HTML] Assessment of antinuclear antibodies (ANA): National recommendations on behalf of the Croatian society of medical biochemistry and laboratory medicine

A Tešija Kuna, L Đerek, V Drvar, A Kozmar… - Biochemia …, 2021 - hrcak.srce.hr
Sažetak Antinuclear antibodies (ANA) represent a family of autoantibodies targeting
ubiquitous cellular constituents and are a hallmark of systemic inflammatory autoimmune …

Anti‐dsDNA, anti‐nucleosome, anti‐C1q, and anti‐histone antibodies as markers of active lupus nephritis and systemic lupus erythematosus disease activity

X Shang, L Ren, G Sun, T Yu, Y Yao… - Immunity …, 2021 - Wiley Online Library
Introduction Previous studies of anti‐dsDNA, nucleosome (Nucl), histone (His), and C1q
antibodies have revealed their clinical value in systemic lupus erythematosus (SLE) …

Applications of neural networks in biomedical data analysis

R Weiss, S Karimijafarbigloo, D Roggenbuck… - Biomedicines, 2022 - mdpi.com
Neural networks for deep-learning applications, also called artificial neural networks, are
important tools in science and industry. While their widespread use was limited because of …

Аутоиммунные ревматические заболевания-проблемы иммунопатологии и персонифицированной терапии

ЕЛ Насонов, ЕН Александрова… - Вестник Российской …, 2015 - cyberleninka.ru
По современным представлениям, аутоиммунитет это комплексный патологический
процесс, в основе которого лежит нарушение толерантности и, как следствие …

Role of autoantibody testing

A Aggarwal - Best Practice & Research Clinical Rheumatology, 2014 - Elsevier
Autoantibodies are the serological hallmark of autoimmune disease. Though their
pathogenic role is debatable, they play an important role in the management of a patient …

The relevance of mass spectrometry analysis for personalized medicine through its successful application in cancer “Omics”

CA Ciocan-Cartita, A Jurj, M Buse, D Gulei… - International Journal of …, 2019 - mdpi.com
Mass spectrometry (MS) is an essential analytical technology on which the emerging omics
domains; such as genomics; transcriptomics; proteomics and metabolomics; are based. This …

Over-Expression of LEDGF/p75 in HEp-2 Cells Enhances Autoimmune IgG Response in Patients with Benign Prostatic Hyperplasia—A Novel Diagnostic Approach …

V Liedtke, L Rose, R Hiemann, A Nasser… - International Journal of …, 2023 - mdpi.com
Lens epithelium-derived growth factor splice variant of 75 kDa (LEDGF/p75) is an
autoantigen over-expressed in solid tumors and acts as a stress-related transcriptional co …