Cerebral hemodynamics and metabolism are frequently impaired in a wide range of
neurological diseases, including traumatic brain injury and stroke, with several …

Non-traumatic subarachnoid hemorrhage (SAH) affects an estimated 30,000 people each
year in the United States, with an overall mortality of~ 30%. Most cases of SAH result from a …

Delayed cerebral vasospasm has classically been considered the most important and
treatable cause of mortality and morbidity in patients with aneurysmal subarachnoid …

Endothelin-1,(ET-1, EDN1) is an endogenous polypeptide which demonstrates dominant
vasoconstriction activity and mitogenic effect. It has positive inotropic and chronotropic …

Cerebral ischemia remains a major cause of morbidity and mortality with little advancement
in subacute treatment options. This review aims to cover and discuss novel insight obtained …

Cerebral vasospasm (CVS) is a potentially lethal complication of aneurysmal subarachnoid
hemorrhage (aSAH). Recently, the symptomatic presentation of CVS has been termed …

Background Mitochondrial dysfunction is related to brain ischemic injury and neural cell
death. However, little is known about the association between mitochondrial dysfunction of …

OBJECTIVE Ischemic complications account for significant patient morbidity following
aneurysmal subarachnoid hemorrhage (aSAH). The Prevention and Treatment of …

Delayed cerebral ischaemia has been described as the single most important cause of
morbidity and mortality in patients who survive the initial aneurysmal subarachnoid …

Aneurysmal subarachnoid hemorrhage (aSAH) may lead to cerebral vasospasm and is
associated with significant morbidity and mortality. It represents a major unmet medical need …