Plasmids, a molecular cornerstone of antimicrobial resistance in the One Health era

S Castañeda-Barba, EM Top, T Stalder - Nature Reviews Microbiology, 2024 - nature.com
Antimicrobial resistance (AMR) poses a substantial threat to human health. The widespread
prevalence of AMR is, in part, due to the horizontal transfer of antibiotic resistance genes …

An overview of plasmid transfer in the plant microbiome

AM Sánchez-Salazar, T Taparia, AK Olesen, JJ Acuña… - Plasmid, 2023 - Elsevier
Plant microbiomes are pivotal for healthy plant physiological development. Microbes live in
complex co-association with plant hosts, and interactions within these microbial …

Estimating the transfer rates of bacterial plasmids with an adapted Luria–Delbrück fluctuation analysis

O Kosterlitz, A Muñiz Tirado, C Wate, C Elg, I Bozic… - PLoS …, 2022 - journals.plos.org
To increase our basic understanding of the ecology and evolution of conjugative plasmids,
we need reliable estimates of their rate of transfer between bacterial cells. Current assays to …

Genomic features and heat resistance profiles of Escherichia coli isolated from Brazilian beef

MAM Machado, VS Castro… - Journal of Applied …, 2023 - academic.oup.com
Abstract Aims Characterize Escherichia coli and E. coli-producing (STEC) isolates from
Brazilian beef to determine heat resistance and the presence of the transmissible locus of …

De Novo Synthesis of a Conjugative System from Human Gut Metagenomic Data for Targeted Delivery of Cas9 Antimicrobials

TA Hamilton, BR Joris, A Shrestha… - ACS Synthetic …, 2023 - ACS Publications
Metagenomic sequences represent an untapped source of genetic novelty, particularly for
conjugative systems that could be used for plasmid-based delivery of Cas9-derived …

[HTML][HTML] Horizontal transmission of a multidrug-resistant IncN plasmid isolated from urban wastewater

Z Yu, Q Wang, R Pinilla-Redondo, JS Madsen… - Ecotoxicology and …, 2024 - Elsevier
Wastewater treatment plants (WWTPs) are considered reservoirs of antibiotic resistance
genes (ARGs). Given that plasmid-mediated horizontal gene transfer plays a critical role in …

Prevention of horizontal transfer of laboratory plasmids to environmental bacteria: comparison of the effectiveness of a few disinfection approaches to degrade DNA

S Loret, B Habib, P Romain, A Roba… - Environmental Science and …, 2023 - Springer
The routine work of any molecular biology laboratory includes the daily use of
microorganisms, including strains of E. coli, transformed with a variety of plasmids …

Transconjugant range of PromA plasmids in microbial communities is predicted by sequence similarity with the bacterial host chromosome

M Tokuda, M Yuki, M Ohkuma… - Microbial …, 2023 - microbiologyresearch.org
Nucleotide sequence similarity, including k-mer plasmid composition, has been used for
prediction of plasmid evolutionary host range, representing the hosts in which a plasmid has …

Ingestible Device for Gastric Fluid Sampling

NK Mandsberg, G Moro, M Ghavami… - Advanced Materials …, 2024 - Wiley Online Library
The composition of the human gastrointestinal microbiota is linked to the health of the host,
and interventions targeting intestinal microbes may thus be designed to prevent or mitigate …

Bacterial Community Composition and Presence of Plasmids in the Endosphere- and Rhizosphere-Associated Microbiota of Sea Fig (Carpobrotus aequilaterus)

AM Sánchez-Salazar, JJ Acuña, MJ Sadowsky… - Diversity, 2023 - mdpi.com
The plant microbiome is one of the most important environments for ecological interactions
between bacteria that impact the plant and the ecosystem. However, studies on the diversity …