Medical treatment of osteoarthritis in the horse–a review

LR Goodrich, AJ Nixon - The Veterinary Journal, 2006 - Elsevier
The medical treatment of osteoarthritis (OA) in the horse is one of the most utilized
therapeutic regimens in the equine practice. It is important to understand the anatomy of …

Joint structure, biochemistry and biochemical disequilibrium in synovitis and equine joint disease.

JL Palmer, AL Bertone - 1994 - cabidigitallibrary.org
This review describes the acute changes thought to occur within the joint during the
inflammatory process, explores how these changes may predispose joint surfaces to further …

Treatment of experimental equine osteoarthritis by in vivo delivery of the equine interleukin-1 receptor antagonist gene

DD Frisbie, SC Ghivizzani, PD Robbins, CH Evans… - Gene therapy, 2002 - nature.com
Osteoarthritis in horses and in humans is a significant social and economic problem and
continued research and improvements in therapy are needed. Because horses have …

Clinical, biochemical, and histologic effects of intra-articular administration of autologous conditioned serum in horses with experimentally induced osteoarthritis

DD Frisbie, CE Kawcak, NM Werpy… - American journal of …, 2007 - Am Vet Med Assoc
Objective—To assess the clinical, biochemical, and histologic effects of intra-articular
administration of autologous conditioned serum (ACS) in the treatment of experimentally …

Effects of triamcinolone acetonide on an in vivo equine osteochondral fragment exercise model

DD Frisbie, CE Kawcak, GW Trotter… - Equine veterinary …, 1997 - Wiley Online Library
The objective of this study was to determine the effects of intra‐articularly administered
triamcinolone acetonide (TA) in exercised equine athletes with carpal osteochondral …

Effects of 6α-methylprednisolone acetate on an equine osteochondral fragment exercise model

DD Frisbie, CE Kawcak, GM Baxter… - American journal of …, 1998 - Am Vet Med Assoc
Objective To determine effects of intra-articularly administered 6α-methylprednisolone
acetate (MPA) in exercised horses with carpal osteochondral fragmentation. Animals 18 …

Contact areas and pressure distribution on the proximal articular surface of the proximal phalanx under sagittal plane loading

PAJ Brama, D Karssenberg, A Barneveld… - Equine veterinary …, 2001 - Wiley Online Library
The objective of this study was to map topographically contact areas and pressure
distributions on the proximal articular surface (PAS) of the proximal phalanx (PI) under …

Evaluation of polysulfated glycosaminoglycan or sodium hyaluronan administered intra-articularly for treatment of horses with experimentally induced osteoarthritis

DD Frisbie, CE Kawcak, CW McIlwraith… - American journal of …, 2009 - Am Vet Med Assoc
Objective—To assess clinical, biochemical, and histologic effects of polysulfated
glycosaminoglycan (PSGAG) or sodium hyaluronan administered intra-articularly in …

Experimentally‐induced synovitis as a model for acute synovitis in the horse

JL Palmer, AL Bertone - Equine veterinary journal, 1994 - Wiley Online Library
The use of extremely small dosages of intra‐articular E. coli lipopolysaccharide (LPS)
endotoxin can create a model of synovitis that mimics acute synovitis in horses. Dosages of …

Synovial fluid gelatinase concentrations and matrix metalloproteinase and cytokine expression in naturally occurring joint disease in horses

TN Trumble, GW Trotter, JRT Oxford… - American journal of …, 2001 - Am Vet Med Assoc
Objectives—To determine concentrations of matrix metalloproteinase (MMP)-2 and-9 in
synovial fluid; and mRNA expression of MMP-1,-13, and-3; interleukin [IL]-1α and β; and …