Psoriasis is a complex long-lasting inflammatory skin disease with high prevalence and
associated comorbidity. It is characterized by epidermal hyperplasia and dermal infiltration …

Several studies have shown that interleukin 6 (IL-6) is a multifunctional cytokine with both
pro-inflammatory and anti-inflammatory activity, depending on the immune response …

Psoriasis is a common inflammatory skin disease involving interactions between
keratinocytes and immune cells that significantly affects the quality of life. It is characterized …

Psoriasis is a chronic, systemic, immune-mediated disease with an incidence of
approximately 2%. The pathogenesis of the disease is complex and not yet fully understood …

Psoriasis is a common, chronic, and inflammatory skin disease with a high burden on
individuals, health systems, and society worldwide. With the immunological pathologies and …

Abstract Background Psoriatic arthritis (PsA) develops in~ 30% of patients with psoriasis.
The diagnosis of PsA is challenging, and there are no reliable molecular markers in clinical …

Psoriasis is a common chronic immune-mediated skin disease characterized by
hyperproliferation and aberrant differentiation of keratinocytes and massive infiltration of …

Psoriasis is an auto-inflammatory skin disease characterized by abnormal activation of
epidermal keratinocytes, aberrant neovascularization, and dysregulation of immune cells …

Autoimmune diseases can be chronic with relapse of inflammatory symptoms, but it can be
also acute and life-threatening if immune cells destroy life-supporting organs, such as lupus …

The observed incidence of psoriasis has been gradually increasing over time (J Am Acad
Dermatol, 03, 2009, 394), but the underlying pathogenic factors have remained unclear …