Medical cannabis activity against inflammation: active compounds and modes of action

SM Anil, H Peeri, H Koltai - Frontiers in pharmacology, 2022 - frontiersin.org
Inflammation often develops from acute, chronic, or auto-inflammatory disorders that can
lead to compromised organ function. Cannabis (Cannabis sativa) has been used to treat …

HIV-associated neurotoxicity and cognitive decline: Therapeutic implications

DR Wallace - Pharmacology & Therapeutics, 2022 - Elsevier
As our understanding of changes to the neurological system has improved, it has become
clear that patients who have contracted human immunodeficiency virus type 1 (HIV-1) can …

Effects of oral cannabinoids on systemic inflammation and viral reservoir markers in people with HIV on antiretroviral therapy: results of the CTN PT028 pilot clinical …

RS Mboumba Bouassa, E Comeau, Y Alexandrova… - Cells, 2023 - mdpi.com
Chronic HIV infection is characterized by persistent inflammation despite antiretroviral
therapy (ART). Cannabinoids may help reduce systemic inflammation in people with HIV …

“The two sides of the same coin”—Medical cannabis, cannabinoids and immunity: Pros and cons explained

M Khoury, I Cohen, G Bar-Sela - Pharmaceutics, 2022 - mdpi.com
Cannabis, as a natural medicinal remedy, has long been used for palliative treatment to
alleviate the side effects caused by diseases. Cannabis-based products isolated from plant …

Cannabinoids modulate the microbiota–gut–brain axis in HIV/SIV infection by reducing neuroinflammation and dysbiosis while concurrently elevating …

M McDew-White, E Lee, LS Premadasa… - Journal of …, 2023 - Springer
Background Although the advent of combination anti-retroviral therapy (cART) has
transformed HIV into a manageable chronic disease, an estimated 30–50% of people living …

[HTML][HTML] Structural and Functional Dysregulation of the Brain Endothelium in HIV Infection and Substance Abuse

N Annadurai, GD Kanmogne - Cells, 2024 - mdpi.com
Blood–brain barrier (BBB) injury and dysfunction following infection with the human
immunodeficiency virus (HIV) enables viral entry into the brain, infection of resident brain …

The Combined Effects of Cannabis, Methamphetamine, and HIV on Neurocognition

JM Rogers, JE Iudicello, MCG Marcondes, EE Morgan… - Viruses, 2023 - mdpi.com
Objective: Methamphetamine and cannabis are two widely used substances among people
living with HIV (PLWH). Whereas methamphetamine use has been found to worsen HIV …

Medical cannabis use and inflammatory cytokines and chemokines among adult chronic pain patients

P Ajrawat, Y Yang, E Wasilewski, T Leroux… - Cannabis and …, 2024 - liebertpub.com
Background: Utilizing cannabis as a therapeutic option for chronic pain (CP) has increased
significantly. However, data regarding the potential immunomodulatory effects of cannabis in …

The role of cannabis and the endocannabinoid system in sleep regulation and cognition: a review of human and animal studies

A Miranda, E Peek, S Ancoli-Israel… - Behavioral Sleep …, 2024 - Taylor & Francis
Objectives Both sleep and cognition are partially modulated by the endocannabinoid (ECB)
system. Cannabis has been reported to have effects on sleep and cognition. This review …

Comparative harms assessments for cannabis, alcohol, and tobacco: Risk for psychosis, cognitive impairment, and traffic accident

PG Johnstad - Drug science, policy and law, 2022 - journals.sagepub.com
Researchers have associated cannabis use with risk for psychosis, cognitive impairment,
and traffic accident. However, this review shows that the association between moderate …