The chirality of small metabolic molecules is important in controlling physiological processes
and indicating the health status of humans. Abnormal enantiomeric ratios of chiral molecules …

The life sciences are currently being transformed by an unprecedented wave of
developments in molecular analysis, which include important advances in instrumental …

Human blood is a self-regenerating lipid-rich biological fluid that is routinely collected in
hospital settings. The inventory of lipid molecules found in blood plasma (plasma lipidome) …

Metabolomics provides a comprehensive assessment of numerous small molecules in
biological samples. As it integrates the effects of exogenous exposures, endogenous …

Metabolomics can be significantly influenced by a range of pre-analytical factors, such as
sample collection, pre-processing, aliquoting, transport, storage and thawing. This therefore …

Micro-RNAs (miRNAs) play a pivotal role in the development and physiology of the
cardiovascular system while they have been associated with multiple cardiovascular …

Background Metabolomics provides measurement of numerous metabolites in human
samples, which can be a useful tool in clinical research. Blood and urine are regarded as …

The stability of lipids and other metabolites in human body fluids ranges from very stable
over several days to very unstable within minutes after sample collection. Since the high …

In analytical chemistry serum as well as plasma are recommended as sample material of
choice. However, blood processing for the generation of serum or plasma is rather different …

The recent thriving development of biobanks and associated high-throughput phenotyping
studies requires the elaboration of large-scale approaches for monitoring biological sample …