Fundamentals of intervertebral disc degeneration
Lumbar disc degeneration is one of the leading causes of chronic low back pain. The
degenerative cascade is often initiated by an imbalance between catabolic and anabolic …
degenerative cascade is often initiated by an imbalance between catabolic and anabolic …
Advanced strategies for the regeneration of lumbar disc annulus fibrosus
Damage to the annulus fibrosus (AF), the outer region of the intervertebral disc (IVD), results
in an undesirable condition that may accelerate IVD degeneration causing low back pain …
in an undesirable condition that may accelerate IVD degeneration causing low back pain …
Annular closure device for disc herniation: meta-analysis of clinical outcome and complications
Background Lumbar intervertebral disc herniation is a common cause of lower back and leg
pain, with surgical intervention (eg discectomy to remove the herniated disc) recommended …
pain, with surgical intervention (eg discectomy to remove the herniated disc) recommended …
The functional role of interface tissue engineering in annulus fibrosus repair: bridging mechanisms of hydrogel integration with regenerative outcomes
TJ DiStefano, JO Shmukler, G Danias… - … biomaterials science & …, 2020 - ACS Publications
Hydrogels are extraordinarily versatile by design and can enhance repair in diseased and
injured musculoskeletal tissues. Biological fixation of these constructs is a significant …
injured musculoskeletal tissues. Biological fixation of these constructs is a significant …
Expert review with meta-analysis of randomized and nonrandomized controlled studies of Barricaid annular closure in patients at high risk for lumbar disc reherniation
LE Miller, RT Allen, B Duhon… - Expert review of medical …, 2020 - Taylor & Francis
Introduction: Patients with lumbar disc herniation and associated sciatica are often referred
for lumbar discectomy. The surgical defect in the annulus fibrosus is typically left unrepaired …
for lumbar discectomy. The surgical defect in the annulus fibrosus is typically left unrepaired …
Intervertebral disc needle puncture injury can be repaired using a gelatin–poly (γ-glutamic acid) hydrogel: an in vitro bovine biomechanical validation
Purpose The subtle impairments of the disc due to anular punctures may have an immediate
effect on the functional integrity due to the altered intradiscal pressure, hence the …
effect on the functional integrity due to the altered intradiscal pressure, hence the …
[HTML][HTML] Interventional Therapy and Surgical Management of Lumbar Disc Herniation in Spine Surgery: A Narrative Review
B Jung, J Han, J Song, A Ngan, D Essig… - Orthopedic …, 2023 - ncbi.nlm.nih.gov
Significant advancements in lumbar disc herniation (LDH) management have been made in
interventional pain therapy, operative therapy, peri-operative management, and cost …
interventional pain therapy, operative therapy, peri-operative management, and cost …
Multilayer electrospun-aligned fibroin/gelatin implant for annulus fibrosus repair: An in vitro and in vivo evaluation
MH Hu, KC Yang, CW Chen, PH Chu, YL Chang… - Biomedicines, 2022 - mdpi.com
Annulus fibrosus (AF) damage is proven to prompt intervertebral disc (IVD) degeneration,
and unrepaired AF lesions after surgical discectomy may boost herniation of the nucleus …
and unrepaired AF lesions after surgical discectomy may boost herniation of the nucleus …
[HTML][HTML] A pilot study of percutaneous interlaminar endoscopic lumbar sequestrectomy: a modern strategy to tackle medically-refractory radiculopathies and restore …
Objective Angled scopes allow 360 visualization, which makes percutaneous endoscopic
techniques (percutaneous endoscopic lumbar discectomy, PELD) particularly attractive for …
techniques (percutaneous endoscopic lumbar discectomy, PELD) particularly attractive for …
Postoperative direct health care costs of lumbar discectomy are reduced with the use of a novel annular closure device in high-risk patients
JD Ament, B Thaci, Z Yang, A Kursumovic… - The Spine Journal, 2019 - Elsevier
ABSTRACT BACKGROUND CONTEXT Lumbar discectomy is largely successful surgical
procedure; however, reherniation rates in patients with large annular defects are as high as …
procedure; however, reherniation rates in patients with large annular defects are as high as …