[HTML][HTML] Molecular Landscape of LncRNAs in Prostate Cancer: A focus on pathways and therapeutic targets for intervention

S Mirzaei, MDA Paskeh, E Okina, MH Gholami… - Journal of Experimental …, 2022 - Springer
Background One of the most malignant tumors in men is prostate cancer that is still incurable
due to its heterogenous and progressive natures. Genetic and epigenetic changes play …

Long non-coding RNAs (lncRNAs) signaling in cancer chemoresistance: from prediction to druggability

GC Eptaminitaki, D Stellas, B Bonavida… - Drug Resistance Updates, 2022 - Elsevier
The acquisition of cancer cell resistance to conventional chemotherapeutics is considered
the major driver of treatment failure and disease recurrence in most solid and hematological …

Long non-coding RNA/epithelial-mesenchymal transition axis in human cancers: Tumorigenesis, chemoresistance, and radioresistance

M Hashemi, S Hajimazdarany, CD Mohan… - Pharmacological …, 2022 - Elsevier
Epithelial-to-mesenchymal transition (EMT) is a process that involves the transformation of
polarized epithelial cells to attain a mesenchymal phenotype that presents an elevated …

A thorough understanding of the role of lncRNA in prostate cancer pathogenesis; Current knowledge and future research directions

R Haghighi, RY Castillo-Acobo, AH Amin… - … -Research and Practice, 2023 - Elsevier
In the entire world, prostate cancer (PCa) is one of the most common and deadly cancers.
Treatment failure is still common among patients, despite PCa diagnosis and treatment …

Non-coding RNAs in EMT regulation: association with tumor progression and therapy response

M Sadrkhanloo, M Entezari, M Rashidi… - European Journal of …, 2022 - Elsevier
RNA molecules lacking capacity in protein translation, are known as non-coding RNAs
(ncRNAs). Growth, differentiation and migration are influenced by ncRNAs in cells. The …

[HTML][HTML] LncRNA FOXP4-AS1 promotes progression of ewing sarcoma and is associated with immune infiltrates

J Xiong, L Wu, L Huang, C Wu, Z Liu, W Deng… - Frontiers in …, 2021 - frontiersin.org
Ewing sarcoma (ES) is a highly malignant primary bone tumor with poor prognosis. Studies
have shown that abnormal expression of lncRNA influences the prognosis of tumor patients …

Anticancer function of microRNA‐30e is mediated by negative regulation of HELLPAR, a noncoding macroRNA, and genes involved in ubiquitination and cell cycle …

K Ganapathy, C Ngo, T Andl, D Coppola… - Molecular …, 2022 - Wiley Online Library
Prostate cancer (PCa) progression relies on androgen receptor (AR) function, making AR a
top candidate for PCa therapy. However, development of drug resistance is common, which …

[HTML][HTML] Importance of long non-coding RNAs in the pathogenesis, diagnosis, and treatment of prostate cancer

M Taheri, E Badrlou, BM Hussen, AH Kashi… - Frontiers in …, 2023 - frontiersin.org
Long non-coding RNAs (lncRNAs) are regulatory transcripts with essential roles in the
pathogenesis of almost all types of cancers, including prostate cancer. They can act as …

[HTML][HTML] Chromogenic in situ hybridization reveals specific expression pattern of long non-coding RNA DRAIC in formalin-fixed paraffin-embedded specimen

K Sakurai, S Yamada, R Ito, M Ochiai, T Ando… - Non-coding RNA …, 2024 - Elsevier
Long non-coding RNA (lncRNA) plays an important role in the regulation of gene expression
in normal and cancer cells. We previously discovered a novel tumor-suppressive lncRNA …

Updated Review on Analysis of long Non-coding RNAs as Emerging Diagnostic and Therapeutic Targets in Prostate Cancers

Z Ke, X Hu, Y Liu, D Shen, MI Khan, J Xiao - Critical Reviews in Oncology …, 2024 - Elsevier
Despite advancements, prostate cancers (PCa) are a significant global health due to
delayed diagnosis and therapeutic resistance. This review delves into the complex …