[HTML][HTML] Molecular Landscape of LncRNAs in Prostate Cancer: A focus on pathways and therapeutic targets for intervention
S Mirzaei, MDA Paskeh, E Okina, MH Gholami… - Journal of Experimental …, 2022 - Springer
Background One of the most malignant tumors in men is prostate cancer that is still incurable
due to its heterogenous and progressive natures. Genetic and epigenetic changes play …
due to its heterogenous and progressive natures. Genetic and epigenetic changes play …
Long non-coding RNAs (lncRNAs) signaling in cancer chemoresistance: from prediction to druggability
GC Eptaminitaki, D Stellas, B Bonavida… - Drug Resistance Updates, 2022 - Elsevier
The acquisition of cancer cell resistance to conventional chemotherapeutics is considered
the major driver of treatment failure and disease recurrence in most solid and hematological …
the major driver of treatment failure and disease recurrence in most solid and hematological …
Long non-coding RNA/epithelial-mesenchymal transition axis in human cancers: Tumorigenesis, chemoresistance, and radioresistance
Epithelial-to-mesenchymal transition (EMT) is a process that involves the transformation of
polarized epithelial cells to attain a mesenchymal phenotype that presents an elevated …
polarized epithelial cells to attain a mesenchymal phenotype that presents an elevated …
A thorough understanding of the role of lncRNA in prostate cancer pathogenesis; Current knowledge and future research directions
In the entire world, prostate cancer (PCa) is one of the most common and deadly cancers.
Treatment failure is still common among patients, despite PCa diagnosis and treatment …
Treatment failure is still common among patients, despite PCa diagnosis and treatment …
Non-coding RNAs in EMT regulation: association with tumor progression and therapy response
M Sadrkhanloo, M Entezari, M Rashidi… - European Journal of …, 2022 - Elsevier
RNA molecules lacking capacity in protein translation, are known as non-coding RNAs
(ncRNAs). Growth, differentiation and migration are influenced by ncRNAs in cells. The …
(ncRNAs). Growth, differentiation and migration are influenced by ncRNAs in cells. The …
[HTML][HTML] LncRNA FOXP4-AS1 promotes progression of ewing sarcoma and is associated with immune infiltrates
J Xiong, L Wu, L Huang, C Wu, Z Liu, W Deng… - Frontiers in …, 2021 - frontiersin.org
Ewing sarcoma (ES) is a highly malignant primary bone tumor with poor prognosis. Studies
have shown that abnormal expression of lncRNA influences the prognosis of tumor patients …
have shown that abnormal expression of lncRNA influences the prognosis of tumor patients …
Anticancer function of microRNA‐30e is mediated by negative regulation of HELLPAR, a noncoding macroRNA, and genes involved in ubiquitination and cell cycle …
K Ganapathy, C Ngo, T Andl, D Coppola… - Molecular …, 2022 - Wiley Online Library
Prostate cancer (PCa) progression relies on androgen receptor (AR) function, making AR a
top candidate for PCa therapy. However, development of drug resistance is common, which …
top candidate for PCa therapy. However, development of drug resistance is common, which …
[HTML][HTML] Importance of long non-coding RNAs in the pathogenesis, diagnosis, and treatment of prostate cancer
Long non-coding RNAs (lncRNAs) are regulatory transcripts with essential roles in the
pathogenesis of almost all types of cancers, including prostate cancer. They can act as …
pathogenesis of almost all types of cancers, including prostate cancer. They can act as …
[HTML][HTML] Chromogenic in situ hybridization reveals specific expression pattern of long non-coding RNA DRAIC in formalin-fixed paraffin-embedded specimen
K Sakurai, S Yamada, R Ito, M Ochiai, T Ando… - Non-coding RNA …, 2024 - Elsevier
Long non-coding RNA (lncRNA) plays an important role in the regulation of gene expression
in normal and cancer cells. We previously discovered a novel tumor-suppressive lncRNA …
in normal and cancer cells. We previously discovered a novel tumor-suppressive lncRNA …
Updated Review on Analysis of long Non-coding RNAs as Emerging Diagnostic and Therapeutic Targets in Prostate Cancers
Z Ke, X Hu, Y Liu, D Shen, MI Khan, J Xiao - Critical Reviews in Oncology …, 2024 - Elsevier
Despite advancements, prostate cancers (PCa) are a significant global health due to
delayed diagnosis and therapeutic resistance. This review delves into the complex …
delayed diagnosis and therapeutic resistance. This review delves into the complex …