Endocytosis in cancer and cancer therapy

B Banushi, SR Joseph, B Lum, JJ Lee… - Nature Reviews …, 2023 - nature.com
Endocytosis is a complex process whereby cell surface proteins, lipids and fluid from the
extracellular environment are packaged, sorted and internalized into cells. Endocytosis is …

[HTML][HTML] Endocytosis: A pivotal pathway for regulating metastasis

I Khan, PS Steeg - British journal of cancer, 2021 - nature.com
A potentially important aspect in the regulation of tumour metastasis is endocytosis. This
process consists of internalisation of cell-surface receptors via pinocytosis, phagocytosis or …

Exosomes, new biomarkers in early cancer detection

SH Jalalian, M Ramezani, SA Jalalian, K Abnous… - Analytical …, 2019 - Elsevier
Exosomes are endosomal-derived vesicles, playing a major role in cell-to-cell
communication. Multiple cells secret these vesicles to induce and inhibit different cellular …

[HTML][HTML] Rab-mediated vesicle trafficking in cancer

HT Tzeng, YC Wang - Journal of biomedical science, 2016 - Springer
A large group of small Rab GTPases which mediate secretory and endosomal membrane
transport, as well as autophagosome biogenesis, are essential components of vesicle …

[HTML][HTML] Hypoxia and extracellular acidification as drivers of melanoma progression and drug resistance

E Dratkiewicz, A Simiczyjew, J Mazurkiewicz, M Ziętek… - Cells, 2021 - mdpi.com
Hypoxia and elevated extracellular acidification are prevalent features of solid tumors and
they are often shown to facilitate cancer progression and drug resistance. In this review, we …

[HTML][HTML] Rab GTPases: switching to human diseases

NA Guadagno, C Progida - Cells, 2019 - mdpi.com
Rab proteins compose the largest family of small GTPases and control the different steps of
intracellular membrane traffic. More recently, they have been shown to also regulate cell …

[HTML][HTML] Rab GTPases: emerging oncogenes and tumor suppressive regulators for the editing of survival pathways in cancer

PD Gopal Krishnan, E Golden, EA Woodward… - Cancers, 2020 - mdpi.com
The Rab GTPase family of proteins are mediators of membrane trafficking, conferring identity
to the cell membranes. Recently, Rab and Rab-associated factors have been recognized as …

The salivary peptide histatin‐1 promotes endothelial cell adhesion, migration, and angiogenesis

P Torres, J Díaz, M Arce, P Silva, P Mendoza… - The FASEB …, 2017 - Wiley Online Library
Saliva is a key factor that contributes to the high efficiency of wound healing in the oral
mucosa. This is not only attributed to physical cues but also to the presence of specific …

Deregulation of Hexokinase II is associated with glycolysis, autophagy, and the epithelial‐mesenchymal transition in tongue squamous cell carcinoma under hypoxia

G Chen, Y Zhang, J Liang, W Li, Y Zhu… - BioMed research …, 2018 - Wiley Online Library
The glycolytic enzyme Hexokinase (HKII) participates in tumor glycolysis and the
progression of various cancers, but its clinicopathological effect on the progression of …

HIF‐1α Regulates the Progression of Cervical Cancer by Targeting YAP/TAZ

A Abudoukerimu, A Hasimu… - Journal of …, 2022 - Wiley Online Library
Cervical carcinoma is one of the serious pernicious cancers that influence women's health.
Invasion and metastasis are the chief reason of poor prognosis of cervical carcinoma …