Single-molecule FRET (smFRET) has become a mainstream technique for studying
biomolecular structural dynamics. The rapid and wide adoption of smFRET experiments by …

Studying dynamics at the single-molecule level enables deeper and more detailed insights
into the behaviors, functions, mechanisms, and heterogeneity of chemical or biological …

Many growth factors and cytokines signal by binding to the extracellular domains of their
receptors and driving association and transphosphorylation of the receptor intracellular …

摘要采用数字微镜器件(DMD) 无掩模光刻技术, 以飞秒激光为光源, 结合大面积拼接的方法快速
制备了具有较高分辨率和毫米尺寸的大面积微纳结构. 提出以单子场投影线扫描的方式进一步 …

Recent advances in nano/microfluidics have led to the miniaturization of surface-based
chemical and biochemical sensors, with applications ranging from environmental monitoring …

The three members of the endocrine-fibroblast growth factor (FGF) family, FGF19, 21, and 23
are circulating hormones that regulate critical metabolic processes. FGF23 stimulates the …

Nanofluidics, a discipline of science and engineering of fluids confined to structures at the 1–
1000 nm scale, has experienced significant growth over the past decade. Nanofluidics have …

Sample preparation is a crucial step in single-molecule experiments and involves
passivating the microfluidic sample chamber, immobilizing the molecules, and setting …

摘要现有主流光刻技术与设备变得越来越复杂的原因之一在于其仍然囿于线性光学光刻范畴,
未能突破光学衍射极限, 是衍射极限附近的光刻技术. 采用紫外, 可见或近红外等长波长光源进行 …

We present a framework for the fabrication of chip-based electrochemical nanogap sensors
integrated with microfluidics. Instead of polydimethylsiloxane (PDMS), SU-8 aided adhesive …