Despite the surgical and chemotherapeutic advances over the past few decades, ovarian
cancer remains the leading cause of gynecological cancer-related mortality. The absence of …

Background Ovarian cancer (OC) is one of the leading causes of cancer related deaths
among women. Due to the asymptomatic tumor progression and lack of efficient screening …

Ovarian cancer has a poor overall survival that is partly caused by resistance to drugs such
as cisplatin. Resistance can be acquired as a result of changes to the tumour or due to …

This article provides an overview of the various research approaches we have explored in
recent years to improve metal-based agents for cancer or infection treatments. Although …

Innate and acquired chemoresistance exhibited by most tumours exposed to conventional
chemotherapeutic agents account for the majority of relapse cases in cancer patients. Such …

There is growing evidence of dysregulated long non-coding RNAs (lncRNAs) serving as
potential biomarkers for cancer prognosis. However, systematic efforts of searching for an …

Gynecological cancers (GCs) are often diagnosed at advanced stages, limiting the efficacy
of available therapeutic options. Thus, there remains an urgent and unmet need for …

Cells naïve to stress can display the effects of stress, such as DNA damage and apoptosis,
when they are exposed to signals from stressed cells; this phenomenon is known as the …

Drug addiction is a chronic and relapsing brain disorder characterized by compulsive drug
seeking and continued drug use despite adverse consequences. The high prevalence and …

In the battle against cancer cells, therapeutic modalities are drastically limited by intrinsic or
acquired drug resistance. Resistance to therapy is not only common, but expected: if …