The BET family in immunity and disease
Innate immunity serves as the rapid and first-line defense against invading pathogens, and
this process can be regulated at various levels, including epigenetic mechanisms. The …
this process can be regulated at various levels, including epigenetic mechanisms. The …
Translating therapeutic microgels into clinical applications
Y Kittel, AJC Kuehne… - Advanced Healthcare …, 2022 - Wiley Online Library
Microgels are crosslinked, water‐swollen networks with a 10 nm to 100 µm diameter and
can be modified chemically or biologically to render them biocompatible for advanced …
can be modified chemically or biologically to render them biocompatible for advanced …
Materials promoting viral gene delivery
K Kaygisiz, CV Synatschke - Biomaterials Science, 2020 - pubs.rsc.org
Therapeutic viral gene delivery is an emerging technology which aims to correct genetic
mutations by introducing new genetic information to cells either to correct a faulty gene or to …
mutations by introducing new genetic information to cells either to correct a faulty gene or to …
[HTML][HTML] Lung cancer and oncolytic virotherapy——enemy's enemy
Z Li, Z Feiyue, L Gaofeng, L Haifeng - Translational Oncology, 2023 - Elsevier
Lung cancer is one of the malignant tumors that seriously threaten human health worldwide,
while the covid-19 virus has become people's nightmare after the coronavirus pandemic …
while the covid-19 virus has become people's nightmare after the coronavirus pandemic …
Nanoassembly with self-regulated magnetic thermal therapy and controlled immuno-modulating agent release for improved immune response
M Gao, K Feng, X Zhang, Y Ruan, G Zhao, H Liu… - Journal of Controlled …, 2023 - Elsevier
Cancer immunotherapy is an emerging cancer therapeutic method by activating the patient's
immune system but suffers from low immunogenicity at tumor sites. Fever-like heat is known …
immune system but suffers from low immunogenicity at tumor sites. Fever-like heat is known …
Nitric oxide polymersome-immobilized hydrogels for prevention of post-surgical tumor recurrence and metastasis
Surgical resection is the primary means of tumor treatment. However, postoperative tumors
are prone to recurrence and metastasis due to residual tumor cells and complicated post …
are prone to recurrence and metastasis due to residual tumor cells and complicated post …
Enzyme-responsive micellar JQ1 induces enhanced BET protein inhibition and immunotherapy of malignant tumors
Z Zhang, Q Zhang, J Xie, Z Zhong, C Deng - Biomaterials Science, 2021 - pubs.rsc.org
Bromodomain and extra-terminal (BET) proteins are attractive targets for treating various
malignancies including melanoma. The inhibition of BET bromodomains, eg with JQ1, is …
malignancies including melanoma. The inhibition of BET bromodomains, eg with JQ1, is …
Recent advances in microfluidic-based cancer immunotherapy-on-a-chip strategies
TK Ngan Ngo, CH Kuo, TY Tu - Biomicrofluidics, 2023 - pubs.aip.org
Despite several extraordinary improvements in cancer immunotherapy, its therapeutic
effectiveness against many distinct cancer types remains mostly limited and requires further …
effectiveness against many distinct cancer types remains mostly limited and requires further …
Gelatin methacryloyl granular scaffolds for localized mRNA delivery
BG Carvalho, A Nakayama, H Miwa, SW Han… - …, 2024 - Wiley Online Library
Messenger RNA (mRNA) therapy is the intracellular delivery of mRNA to produce desired
therapeutic proteins. Developing strategies for local mRNA delivery is still required where …
therapeutic proteins. Developing strategies for local mRNA delivery is still required where …
[HTML][HTML] Progress in oncolytic viruses modified with nanomaterials for intravenous application
L Chen, Z Ma, C Xu, Y Xie, D Ouyang… - Cancer Biology & …, 2023 - ncbi.nlm.nih.gov
In oncolytic virus (OV) therapy, a critical component of tumor immunotherapy, viruses
selectively infect, replicate within, and eventually destroy tumor cells. Simultaneously, this …
selectively infect, replicate within, and eventually destroy tumor cells. Simultaneously, this …