Cerebral small vessel disease (SVD) is common during ageing and can present as stroke,
cognitive decline, neurobehavioural symptoms, or functional impairment. SVD frequently …

Treatments for Alzheimer's disease (AD) directed against the prominent amyloid plaque
neuropathology are yet to be proved effective despite many phase 3 clinical trials. There are …

Ferroptosis is an iron-dependent form of regulated cell death with distinct characteristics,
including altered iron homeostasis, reduced defense against oxidative stress, and abnormal …

Ferroptosis is a form of regulated cell death characterized by the iron-dependent
accumulation of lipid hydroperoxides to lethal levels. Emerging evidence suggests that …

Alzheimer's disease (AD) is a progressive neurodegenerative disease with a complex and
heterogeneous pathophysiology. The number of people living with AD is predicted to …

Alzheimer's disease (AD) is the most prevalent form of dementia, with complex
pathophysiology that is not fully understood. While β‐amyloid plaque and neurofibrillary …

Perturbations in iron homeostasis and iron accumulation feature in several
neurodegenerative disorders including Alzheimer's disease (AD), Parkinson's disease (PD) …

Ferroptosis is a newly described form of regulated cell death, distinct from apoptosis,
necroptosis and other forms of cell death. Ferroptosis is induced by disruption of glutathione …

Iron has been increasingly implicated in the pathology of neurodegenerative diseases. In
the past decade, development of the new magnetic resonance imaging technique …

Cortical iron has been shown to be elevated in Alzheimer's disease (AD), but the impact of
the directly measured iron on the clinical syndrome has not been assessed. We investigated …