Emerging applications of nanotechnology in healthcare systems: Grand challenges and perspectives

S Anjum, S Ishaque, H Fatima, W Farooq, C Hano… - Pharmaceuticals, 2021 - mdpi.com
Healthcare, as a basic human right, has often become the focus of the development of
innovative technologies. Technological progress has significantly contributed to the …

Synthetic materials at the forefront of gene delivery

I Lostalé-Seijo, J Montenegro - Nature Reviews Chemistry, 2018 - nature.com
The delivery of nucleic acids with transient activity for genetic engineering is a promising
methodology with potential applications in the treatment of diseases ranging from cancer …

Microporous methacrylated glycol chitosan-montmorillonite nanocomposite hydrogel for bone tissue engineering

ZK Cui, S Kim, JJ Baljon, BM Wu, T Aghaloo… - Nature …, 2019 - nature.com
Injectable hydrogels can fill irregular defects and promote in situ tissue regrowth and
regeneration. The ability of directing stem cell differentiation in a three-dimensional …

Materials-based nanotherapeutics for injured and diseased bone

CS Lee, RK Singh, HS Hwang, NH Lee… - Progress in Materials …, 2023 - Elsevier
Severe injuries and diseases of bone tissue caused by congenital disorder, extrinsic trauma,
infection, and osteosarcoma resection face significant challenges for complete recovery. The …

Lipid nanovesicles for biomedical applications:'What is in a name'?

AC Apolinário, L Hauschke, JR Nunes… - Progress in lipid research, 2021 - Elsevier
Vesicles, generally defined as self-assembled structures formed by single or multiple
concentric bilayers that surround an aqueous core, have been widely used for biomedical …

Bioactive scaffolds integrated with liposomal or extracellular vesicles for bone regeneration

M Kang, CS Lee, M Lee - Bioengineering, 2021 - mdpi.com
With population aging and increased life expectancy, an increasing number of people are
facing musculoskeletal health problems that necessitate therapeutic intervention at defect …

Nanomaterials modulate stem cell differentiation: biological interaction and underlying mechanisms

M Wei, S Li, W Le - Journal of nanobiotechnology, 2017 - Springer
Stem cells are unspecialized cells that have the potential for self-renewal and differentiation
into more specialized cell types. The chemical and physical properties of surrounding …

RNA interfering molecule delivery from in situ forming biodegradable hydrogels for enhancement of bone formation in rat calvarial bone defects

MK Nguyen, O Jeon, PN Dang, CT Huynh, D Varghai… - Acta biomaterialia, 2018 - Elsevier
RNA interference (RNAi) may be an effective and valuable tool for promoting the growth of
functional tissue, as short interfering RNA (siRNA) and microRNA (miRNA) can block the …

Non-viral gene activated matrices for mesenchymal stem cells based tissue engineering of bone and cartilage

S Raisin, E Belamie, M Morille - Biomaterials, 2016 - Elsevier
Recent regenerative medicine and tissue engineering strategies for bone and cartilage
repair have led to fascinating progress of translation from basic research to clinical …

Non-coding RNA delivery for bone tissue engineering: Progress, challenges, and potential solutions

S Guan, Z Zhang, J Wu - Iscience, 2022 - cell.com
More than 20 million individuals worldwide suffer from congenital or acquired bone defects
annually. The development of bone scaffold materials that simulate natural bone for bone …