Biological drugs generated via recombinant techniques are uniquely positioned due to their
high potency and high selectivity of action. The major drawback of this class of therapeutics …

Controlling the bulk and surface properties of materials is a real challenge for bioengineers
working in the fields of biomaterials, tissue engineering and biophysics. The layer-by-layer …

The regeneration of bone tissue is regulated by both osteogenic and angiogenic growth
factors which are expressed in a coordinated cascade of events. The aim of this study was to …

Bone morphogenetic protein-2 (BMP-2) is a potent osteoinductive cytokine that plays a
critical role during bone regeneration and repair. In the extracellular environment, sulfated …

Polymer films and coatings are among the popular and most successful tools to modulate
surface properties of biomaterials, specifically tissue responses and fouling behavior. Over …

In recent years, the layer-by-layer technique has grown in various fields. One of the
emerging trends of bio-applications is the use of polysaccharides as main film components …

Surface modification of biomaterials is a well‐known approach to enable an adequate
biointerface between the implant and the surrounding tissue, dictating the initial acceptance …

Calcium phosphate cement scaffold (CPC) has been widely used as bone graft substitutes,
but undesirable osteoinductivity and slow degradability greatly hamper their clinic …

Delivering rhBMP-2 (recombinant Bone Morphogenic Protein-2) at low but therapeutically
efficient dose is one of the current challenges for bone tissue repair. In this context …

A simple method for the functionalization of a common implant material (Ti6Al4V) with
biodegradable, drug loaded chitosan-tripolyphosphate (CS-TPP) nanoparticles is …