The large GTP ase dynamin is the first protein shown to catalyze membrane fission.
Dynamin and its related proteins are essential to many cell functions, from endocytosis to …

The Mx dynamin-like GTPases are key antiviral effector proteins of the type I and type III
interferon (IFN) systems. They inhibit several different viruses by blocking early steps of the …

Mitochondria are double-membraned organelles with variable shapes influenced by
metabolic conditions, developmental stage, and environmental stimuli,,,. Their dynamic …

Dynamin superfamily proteins are multidomain mechano‐chemical GTPases which are
implicated in nucleotide‐dependent membrane remodeling events. A prominent feature of …

The human MxA protein, encoded by the interferon-inducible MX1 gene, is an intracellular
influenza A virus (IAV) restriction factor. It can protect transgenic mice from severe IAV …

Interferon (IFN)-related DNA damage resistant signature (IRDS) genes are a subgroup of
interferon-stimulated genes (ISGs) found upregulated in different cancer types, which …

The IFN-induced human myxovirus resistance protein A (MxA) exhibits a broad antiviral
activity against many viruses, including influenza A virus (IAV). MxA belongs to the family of …

Interferons limit viral replication by inducing intracellular restriction factors, such as the
GTPase MxB (also designated MX2), which inhibits HIV-1 and, as recently shown …

We have employed molecular genetic approaches to understand the domain organization of
the HIV-1 resistance factor myxovirus resistance 2 (MX2). First, we describe an essential …

Dynamin‐related proteins are multidomain, mechanochemical GTPases that self‐assemble
and orchestrate a wide array of cellular processes. Over the past decade, structural insights …