EffectorP 3.0: prediction of apoplastic and cytoplasmic effectors in fungi and oomycetes

J Sperschneider, PN Dodds - Molecular plant-microbe …, 2022 - Am Phytopath Society
Many fungi and oomycete species are devasting plant pathogens. These eukaryotic
filamentous pathogens secrete effector proteins to facilitate plant infection. Fungi and …

Bioinformatic prediction of plant–pathogenicity effector proteins of fungi

DAB Jones, S Bertazzoni, CJ Turo, RA Syme… - Current opinion in …, 2018 - Elsevier
Highlights•Review of current methods in fungal plant pathogenicity effector protein
prediction.•Recent advances have been made in structural and machine learning-based …

Improved prediction of fungal effector proteins from secretomes with EffectorP 2.0

J Sperschneider, PN Dodds… - Molecular plant …, 2018 - Wiley Online Library
Plant‐pathogenic fungi secrete effector proteins to facilitate infection. We describe extensive
improvements to EffectorP, the first machine learning classifier for fungal effector prediction …

LOCALIZER: subcellular localization prediction of both plant and effector proteins in the plant cell

J Sperschneider, AM Catanzariti, K DeBoer, B Petre… - Scientific reports, 2017 - nature.com
Pathogens secrete effector proteins and many operate inside plant cells to enable infection.
Some effectors have been found to enter subcellular compartments by mimicking host …

Seeking the interspecies crosswalk for filamentous microbe effectors

N Stuer, P Van Damme, S Goormachtig… - Trends in Plant …, 2023 - cell.com
Both pathogenic and symbiotic microorganisms modulate the immune response and
physiology of their host to establish a suitable niche. Key players in mediating colonization …

ApoplastP: prediction of effectors and plant proteins in the apoplast using machine learning

J Sperschneider, PN Dodds, KB Singh… - New …, 2018 - Wiley Online Library
The plant apoplast is integral to intercellular signalling, transport and plant–pathogen
interactions. Plant pathogens deliver effectors both into the apoplast and inside host cells …

Computational Structural Genomics Unravels Common Folds and Novel Families in the Secretome of Fungal Phytopathogen Magnaporthe oryzae

K Seong, KV Krasileva - Molecular Plant-Microbe Interactions, 2021 - Am Phytopath Society
Structural biology has the potential to illuminate the evolution of pathogen effectors and their
commonalities that cannot be readily detected at the primary sequence level. Recent …

Key processes required for the different stages of fungal carnivory by a nematode-trapping fungus

HC Lin, GVD de Ulzurrun, SA Chen, CT Yang… - PLoS …, 2023 - journals.plos.org
Nutritional deprivation triggers a switch from a saprotrophic to predatory lifestyle in soil-
dwelling nematode-trapping fungi (NTF). In particular, the NTF Arthrobotrys oligospora …

Genomic, network, and phylogenetic analysis of the oomycete effector arsenal

J McGowan, DA Fitzpatrick - MSphere, 2017 - Am Soc Microbiol
The oomycetes are a class of microscopic, filamentous eukaryotes within the stramenopiles-
alveolate-Rhizaria (SAR) supergroup and include ecologically significant animal and plant …

The structural landscape and diversity of Pyricularia oryzae MAX effectors revisited

M Lahfa, P Barthe, K De Guillen, S Cesari… - PLoS …, 2024 - journals.plos.org
Magnaporthe AVRs and ToxB-like (MAX) effectors constitute a family of secreted virulence
proteins in the fungus Pyricularia oryzae (syn. Magnaporthe oryzae), which causes blast …